The ability to adaptively regulate emotion is essential for mental and physical well-being.
How should we organize the myriad ways people attempt to regulate their emotions? We …

The term 'stress'–coined in 1936–has many definitions, but until now has lacked a
theoretical foundation. Here we present an information-theoretic approach–based on the …

Biomarkers have transformed modern medicine but remain largely elusive in psychiatry,
partly because there is a weak correspondence between diagnostic labels and their …

The prefrontal cortex (PFC) plays a critical role in the generation and regulation of emotion.
However, we lack an integrative framework for understanding how different emotion-related …

BACKGROUND It is widely believed that the human sense of smell is inferior to that of other
mammals, especially rodents and dogs. This Review traces the scientific history of this idea …

This article provides a review of the increasingly detailed imaging literature on the
neurodevelopment of joint attention. Many findings from this literature support and inform the …

Pleasure is mediated by well-developed mesocorticolimbic circuitry and serves adaptive
functions. In affective disorders, anhedonia (lack of pleasure) or dysphoria (negative affect) …

Numerous studies have begun to address how the brain's gray and white matter may be
shaped by meditation. This research is yet to be integrated, however, and two fundamental …

In this review, we summarize findings supporting the existence of multiple behavioral
strategies for controlling reward-related behavior, including a dichotomy between the goal …

The number of papers about the orbitofrontal cortex (OFC) has grown from 1 per month in
1987 to a current rate of over 50 per month. This publication stream has implicated the OFC …