Abstract Oleanolic acid (OA, 3 β-hydroxyoleanolic acid-12-en-28-oic acid) is a pentacyclic
triterpenoid present in many plants. As a new framework for development of semi synthetic …

Oximes have been studied for decades because of their significant roles as
acetylcholinesterase reactivators. Over the last twenty years, a large number of oximes have …

Oleanolic acid (OA), a ubiquitous pentacyclic oleanane-type triterpene isolated from edible
and medicinal plants, exhibits a wide spectrum of pharmacological activities and …

The pentacyclic triterpenes represent a significant class of plant bioactives with a variety of
structures and a wide array of biological activities. These are biosynthetically produced via …

Naturally occurring pentacyclic triterpenoid oleanolic acid (OA) serves as a good scaffold for
additional modifications to achieve synthetic derivatives. Therefore, a large number of …

Liver-associated diseases affect millions of individuals worldwide. In developed countries,
the incidence of viral hepatitis is reducing due to advancements in disease prevention …

At the end of 2019, a novel virus causing severe acute respiratory syndrome to spread
globally. There are currently no effective drugs targeting SARS-CoV-2. In this study, based …

Oleanolic acid (OA) is a vegetable chemical that is present naturally in a number of edible
and medicinal botanicals. It has been extensively studied by medicinal chemists and …

In this study, 13 new hybrid compounds were synthesized starting from the natural product
oleanolic acid and their in vitro cytotoxic activities were investigated on the BEAS-2B and …

Here, an amphiphilic polymer, oleanolic acid conjugated methoxy-poly (ethylene glycol)-
poly (D, l-lactide)(mPEG-PLA-OA) was synthesized, which self-assembled in aqueous …