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miRNAs: potential as biomarkers and therapeutic targets for cancer
MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that regulate gene
expression post-transcriptionally by binding to messenger RNAs. miRNAs are important …
expression post-transcriptionally by binding to messenger RNAs. miRNAs are important …
Epigenetics of colorectal cancer: biomarker and therapeutic potential
G Jung, E Hernández-Illán, L Moreira… - Nature reviews …, 2020 - nature.com
Colorectal cancer (CRC), a leading cause of cancer-related death worldwide, evolves as a
result of the stepwise accumulation of a series of genetic and epigenetic alterations in the …
result of the stepwise accumulation of a series of genetic and epigenetic alterations in the …
[HTML][HTML] From molecular mechanisms to therapeutics: understanding MicroRNA-21 in cancer
J Rhim, W Baek, Y Seo, JH Kim - Cells, 2022 - mdpi.com
MicroRNAs (miRNAs) are small noncoding RNAs that play an important role in regulating
gene expression at a posttranscriptional level. As one of the first discovered oncogenic …
gene expression at a posttranscriptional level. As one of the first discovered oncogenic …
Epigenetic regulation in hematopoiesis and its implications in the targeted therapy of hematologic malignancies
A Zhao, H Zhou, J Yang, M Li, T Niu - Signal transduction and targeted …, 2023 - nature.com
Hematologic malignancies are one of the most common cancers, and the incidence has
been rising in recent decades. The clinical and molecular features of hematologic …
been rising in recent decades. The clinical and molecular features of hematologic …
ncRNA-encoded peptides or proteins and cancer
J Wang, S Zhu, N Meng, Y He, R Lu, GR Yan - Molecular Therapy, 2019 - cell.com
Non-coding RNAs (ncRNAs) are unique RNA transcripts that have been widely identified in
the eukaryotic genome and have been shown to play key roles in the development of many …
the eukaryotic genome and have been shown to play key roles in the development of many …
Epigenetic alterations in colorectal cancer: emerging biomarkers
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …
fundamental processes driving the initiation and progression of CRC is the accumulation of …
PBMDA: A novel and effective path-based computational model for miRNA-disease association prediction
In the recent few years, an increasing number of studies have shown that microRNAs
(miRNAs) play critical roles in many fundamental and important biological processes. As …
(miRNAs) play critical roles in many fundamental and important biological processes. As …
Genetics and genetic biomarkers in sporadic colorectal cancer
JM Carethers, BH Jung - Gastroenterology, 2015 - Elsevier
Sporadic colorectal cancer (CRC) is a somatic genetic disease in which pathogenesis is
influenced by the local colonic environment and the patient's genetic background …
influenced by the local colonic environment and the patient's genetic background …
MicroRNA and cancer–a brief overview
MicroRNAs (miRNAs) are short non-coding RNAs with a length of∼ 22 nucleotides,
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …
Role of microRNAs in translation regulation and cancer
MicroRNAs (miRNAs) are pervasively expressed and regulate most biological functions.
They function by modulating transcriptional and translational programs and therefore they …
They function by modulating transcriptional and translational programs and therefore they …