Intermediate filament (IF) proteins make up the largest family of cytoskeletal proteins in
metazoans, and are traditionally known for their roles in fostering structural integrity in cells …

Intermediate filaments are cytoskeletal polymers encoded by a large family of differentially
expressed genes that provide crucial structural support in the cytoplasm and nucleus of …

Keratins are cytoplasmic intermediate filament proteins preferentially expressed by epithelial
tissues in a site-specific and differentiation-dependent manner. The complex network of …

Putative epithelial stem cells in the hair follicle bulge are thought to play pivotal roles in the
homeostasis, aging, and carcinogenesis of the cutaneous epithelium. Elucidating the role of …

The diversity of epithelial functions is reflected by the expression of distinct keratin pairs that
are responsible to protect epithelial cells against mechanical stress and to act as signaling …

Intermediate filaments (IFs) are cytoskeletal polymers whose protein constituents are
encoded by a large family of differentially expressed genes. Owing in part to their properties …

Abstract Protein kinase B (PKB/Akt) is a serine/threonine protein kinase that created serious
interest when it was revealed as a mediator of the PI3K pathway. It comprises three isoforms …

Keratins, the major structural protein of all epithelia are a diverse group of cytoskeletal
scaffolding proteins that form intermediate filament networks, providing structural support to …

Differentiation of skin stem cells into hair follicles (HFs) requires the inhibition of β-catenin
degradation, which is controlled by a complex containing axin and the protein kinase …

Migration of epithelial cells is fundamental to multiple developmental processes, epithelial
tissue morphogenesis and maintenance, wound healing and metastasis. While migrating …