Diet has a pivotal role in sha** the composition, function and diversity of the gut
microbiome, with various diets having a profound impact on the stability, functionality and …

Chronic kidney disease (CKD) is defined by a low glomerular filtration rate or high
albuminuria, and affects 15–20% of adults globally. CKD increases the risk of various …

Numerous studies have indicated that the progression of chronic kidney disease (CKD) to
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …

Objective Patients with renal failure suffer from symptoms caused by uraemic toxins,
possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is …

Objective to investigate whether diets differing in fat content alter the gut microbiota and
faecal metabolomic profiles, and to determine their relationship with cardiometabolic risk …

Complex diseases, such as coronary artery disease (CAD), are often multifactorial, caused
by multiple underlying pathological mechanisms. Here, to study the multifactorial nature of …

Significant interest in recent years has focused on gut microbiota–host interaction because
accumulating evidence has revealed that intestinal microbiota play an important role in …

The kidney harbours different types of endothelia, each with specific structural and functional
characteristics. The glomerular endothelium, which is highly fenestrated and covered by a …

It is widely accepted that obesity and associated metabolic diseases, including type 2
diabetes, are intimately linked to diet. However, the gut microbiota has also become a focus …

The gut microbiota is a highly complex community which evolves and adapts to its host over
a lifetime. It has been described as a virtual organ owing to the myriad of functions it …