Procalcitonin (PCT) is a protein that consists of 116 amino acids and is the peptide precursor
of calcitonin. Calcitonin is initially biosynthesized as PCT, which, under normal conditions, is …

Every year numerous individuals develop the morbid condition of sepsis. Therefore, novel
biomarkers that might better inform clinicians treating such patients are sorely needed …

Background The global burden of sepsis is estimated as 15 to 19 million cases annually,
with a mortality rate approaching 60% in low-income countries. Methods In this retrospective …

Background Sepsis is a major public health burden resulting in 25% to 30% in-hospital
mortality and accounting for over 20 billion dollars of US hospital costs. Research Question …

Abstract Background Since the Sepsis-3 criteria, change in Sequential Organ Failure
Assessment (SOFA) score has become a key component of sepsis identification. Thus, it …

Objective The primary objective of this study was to determine the correlation between
procalcitonin values and illness severity by evaluating the degree of end organ dysfunction …

Immune therapy to ease the burden of sepsis has thus far failed to consistently improve
patient outcomes. Advances in cancer immune therapy and awareness that prolonged …

Purpose The purpose of the study was to quantify the ability of procalcitonin (PCT) and
interleukin-6 (IL-6) to differentiate noninfectious systemic inflammatory response syndrome …

Sepsis is a major source of mortality and morbidity globally. Accurately diagnosing sepsis
remains challenging due to the heterogeneous nature of the disease, and delays in …

Objective This study comparatively evaluated the value of dynamic procalcitonin (PCT) and
presepsin measurements in assessing therapeutic efficacy and prognosis for patients with …