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Human liver cancer organoids: Biological applications, current challenges, and prospects in hepatoma therapy
L Chen, X Wei, D Gu, Y Xu, H Zhou - Cancer Letters, 2023 - Elsevier
Liver cancer and disease are among the most socially challenging global health concerns.
Although organ transplantation, surgical resection and anticancer drugs are the main …
Although organ transplantation, surgical resection and anticancer drugs are the main …
Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after TH2-biased immunization
A Ebenig, S Muraleedharan, J Kazmierski, D Todt… - Cell reports, 2022 - cell.com
Vaccine-associated enhanced respiratory disease (VAERD) is a severe complication for
some respiratory infections. To investigate the potential for VAERD induction in coronavirus …
some respiratory infections. To investigate the potential for VAERD induction in coronavirus …
Cost of universality: A comparative study of the overhead of state distillation and code switching with color codes
Estimating and reducing the overhead of fault-tolerance (FT) schemes is a crucial step
toward realizing scalable quantum computers. Of particular interest are schemes based on …
toward realizing scalable quantum computers. Of particular interest are schemes based on …
The diverse roles of peroxisomes in the interplay between viruses and mammalian cells
Peroxisomes are ubiquitous organelles found in eukaryotic cells that play a critical role in
the oxidative metabolism of lipids and detoxification of reactive oxygen species (ROS) …
the oxidative metabolism of lipids and detoxification of reactive oxygen species (ROS) …
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution
The accessory protease transmembrane protease serine 2 (TMPRSS2) enhances severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uptake into ACE2-expressing …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uptake into ACE2-expressing …
Targeting cellular cathepsins inhibits hepatitis E virus entry
M Klöhn, T Burkard, J Janzen, JA Haase, A Gömer… - Hepatology, 2024 - journals.lww.com
Conclusions: In summary, our study highlights the pivotal role of lysosomal cathepsins,
especially CTSL, in the HEV entry process. The profound anti-HEV efficacy of the pan …
especially CTSL, in the HEV entry process. The profound anti-HEV efficacy of the pan …
Universal fault-tolerant measurement-based quantum computation
Certain physical systems that one might consider for fault-tolerant quantum computing
where qubits do not readily interact, for instance photons, are better suited for measurement …
where qubits do not readily interact, for instance photons, are better suited for measurement …
MicroRNAs modulate SARS‐CoV‐2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2
Abstract Background and Aims Severe acute respiratory syndrome coronavirus (SARS‐CoV‐
2) preferentially infects the respiratory tract; however, several studies have implicated a multi …
2) preferentially infects the respiratory tract; however, several studies have implicated a multi …
Implementation of a controlled human infection model for evaluation of HCV vaccine candidates
Hepatitis C virus (HCV) remains a major global health concern. Directly acting antiviral
(DAA) drugs have transformed the treatment of HCV. However, it has become clear that …
(DAA) drugs have transformed the treatment of HCV. However, it has become clear that …
A C-type lectin-like receptor CD302 in yellow drum (Nibea albiflora) functioning in antibacterial activity and innate immune signaling
J Peng, J Li, J Liang, W Li, Y Yang, Y Yang… - International Journal of …, 2023 - Elsevier
Molecular dissection of disease resistance against Vibrio harveyi infection in yellow drum at
the genome-wide level uncovered a C-type lectin-like receptor cluster of differentiation …
the genome-wide level uncovered a C-type lectin-like receptor cluster of differentiation …