[HTML][HTML] Impact of alcohol abuse on the adaptive immune system
S Pasala, T Barr, I Messaoudi - Alcohol research: current reviews, 2015 - ncbi.nlm.nih.gov
Alcohol exposure, and particularly chronic heavy drinking, affects all components of the
adaptive immune system. Studies both in humans and in animal models determined that …
adaptive immune system. Studies both in humans and in animal models determined that …
[HTML][HTML] Cell-mediated protection in influenza infection
PG Thomas, R Keating, DJ Hulse-Post… - Emerging infectious …, 2006 - ncbi.nlm.nih.gov
Current vaccine strategies against influenza focus on generating robust antibody responses.
Because of the high degree of antigenic drift among circulating influenza strains over the …
Because of the high degree of antigenic drift among circulating influenza strains over the …
A distinct function of regulatory T cells in tissue protection
Regulatory T (Treg) cells suppress immune responses to a broad range of non-microbial
and microbial antigens and indirectly limit immune inflammation-inflicted tissue damage by …
and microbial antigens and indirectly limit immune inflammation-inflicted tissue damage by …
Human CD8+ T cell cross-reactivity across influenza A, B and C viruses
Abstract Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally and
infect humans, with IAV and IBV causing the most severe disease. CD8+ T cells confer cross …
infect humans, with IAV and IBV causing the most severe disease. CD8+ T cells confer cross …
[HTML][HTML] Essential role of IL-6 in protection against H1N1 influenza virus by promoting neutrophil survival in the lung
O Dienz, JG Rud, SM Eaton, PA Lanthier, E Burg… - Mucosal …, 2012 - Elsevier
Influenza virus infection is considered a major worldwide public health problem. Seasonal
infections with the most common influenza virus strains (eg, H1N1) can usually be resolved …
infections with the most common influenza virus strains (eg, H1N1) can usually be resolved …
Natural T cell–mediated protection against seasonal and pandemic influenza. Results of the flu watch cohort study
Rationale: A high proportion of influenza infections are asymptomatic. Animal and human
challenge studies and observational studies suggest T cells protect against disease among …
challenge studies and observational studies suggest T cells protect against disease among …
[HTML][HTML] IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms
AJ Macpherson, L Hunziker, K McCoy, A Lamarre - Microbes and infection, 2001 - Elsevier
IgA is the most abundant immunoglobulin produced in mammals; most is secreted as a
dimer across mucous membranes. This review discusses the different mechanisms of …
dimer across mucous membranes. This review discusses the different mechanisms of …
CD8 T cells utilize TRAIL to control influenza virus infection
EL Brincks, A Katewa, TA Kucaba… - The Journal of …, 2008 - journals.aai.org
Elimination of influenza virus-infected cells during primary influenza virus infections is
thought to be mediated by CD8+ T cells though perforin-and FasL-mediated mechanisms …
thought to be mediated by CD8+ T cells though perforin-and FasL-mediated mechanisms …
Identification of SARS-CoV-2 vaccine epitopes predicted to induce long-term population-scale immunity
Here we propose a SARS-CoV-2 vaccine design concept based on identification of highly
conserved regions of the viral genome and newly acquired adaptations, both predicted to …
conserved regions of the viral genome and newly acquired adaptations, both predicted to …
Memory CD4 T cells direct protective responses to influenza virus in the lungs through helper-independent mechanisms
Memory CD4 T cells specific for influenza virus are generated from natural infection and
vaccination, persist long-term, and recognize determinants in seasonal and pandemic …
vaccination, persist long-term, and recognize determinants in seasonal and pandemic …