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Metabolic engineering for increased lipid accumulation in Yarrowia lipolytica–a review
Current energy security and climate change policies encourage the development and
utilization of bioenergy. Oleaginous yeasts provide a particularly attractive platform for the …
utilization of bioenergy. Oleaginous yeasts provide a particularly attractive platform for the …
Aflatoxin detoxification using microorganisms and enzymes
Y Guan, J Chen, E Nepovimova, M Long, W Wu… - Toxins, 2021 - mdpi.com
Mycotoxin contamination causes significant economic loss to food and feed industries and
seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins …
seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins …
Engineering oxidative stress defense pathways to build a robust lipid production platform in Yarrowia lipolytica
Microbially derived lipids have recently attracted renewed interests due to their broad
applications in production of green diesels, cosmetic additives, and oleochemicals …
applications in production of green diesels, cosmetic additives, and oleochemicals …
Strategies and challenges for the development of industrial enzymes using fungal cell factories
J Arnau, D Yaver, CM Hjort - Grand challenges in fungal biotechnology, 2020 - Springer
Industrial enzymes have been produced from microorganisms for more than a century.
Today, a large share of enzyme products is manufactured using recombinant …
Today, a large share of enzyme products is manufactured using recombinant …
Elucidation of triacylglycerol catabolism in Yarrowia lipolytica: How cells balance acetyl-CoA and excess reducing equivalents
Yarrowia lipolytica is an industrial yeast that can convert waste oil to value-added products.
However, it is unclear how this yeast metabolizes lipid feedstocks, specifically triacylglycerol …
However, it is unclear how this yeast metabolizes lipid feedstocks, specifically triacylglycerol …
Aflatoxin biodetoxification strategies based on postbiotics
Aflatoxins (AFs) are secondary metabolites produced by fungi, and they are deemed the
most perilous mycotoxin and food safety predicament. The exposure of humans to …
most perilous mycotoxin and food safety predicament. The exposure of humans to …
Citric acid and itaconic acid accumulation: variations of the same story?
Citric acid production by Aspergillus niger and itaconic acid production by Aspergillus
terreus are two major examples of technical scale fungal fermentations based on metabolic …
terreus are two major examples of technical scale fungal fermentations based on metabolic …
Metabolic engineering of Aspergillus niger for accelerated malic acid biosynthesis by improving NADPH availability
N Wu, X Wu, M Zhang, C Zhang, Q Xu - Biotechnology Journal, 2024 - Wiley Online Library
Microbial production of L‐malic acid from renewable carbon sources has attracted extensive
attention. The reduced cofactor NADPH plays a key role in biotransformation because it …
attention. The reduced cofactor NADPH plays a key role in biotransformation because it …
[HTML][HTML] Multi-omics view of recombinant Yarrowia lipolytica: Enhanced ketogenic amino acid catabolism increases polyketide-synthase-driven docosahexaenoic …
SJ Gasovic, D Dietrich, L Gläser, P Cao… - Metabolic …, 2023 - Elsevier
DHA is a marine PUFA of commercial value, given its multiple health benefits. The
worldwide emerging shortage in DHA supply has increased interest in microbial cell …
worldwide emerging shortage in DHA supply has increased interest in microbial cell …
Recent advances in biotechnological production of polyunsaturated fatty acids by Yarrowia lipolytica
Owing to the important physiological functions, polyunsaturated fatty acids (PUFAs) play a
vital role in protecting human health, such as preventing cancer, cardiovascular disease …
vital role in protecting human health, such as preventing cancer, cardiovascular disease …