Recent development in beta titanium alloys for biomedical applications

LY Chen, YW Cui, LC Zhang - Metals, 2020‏ - mdpi.com
β-type titanium (Ti) alloys have attracted a lot of attention as novel biomedical materials in
the past decades due to their low elastic moduli and good biocompatibility. This article …

Powder metallurgy with space holder for porous titanium implants: A review

A Rodriguez-Contreras, M Punset, JA Calero… - Journal of Materials …, 2021‏ - Elsevier
One of the biggest challenges in the biocompatibility of implantable metals is the prevention
of the stress shielding effect, which is related to the coupling of the bone-metal mechanical …

Biomaterial-based regional chemotherapy: Local anticancer drug delivery to enhance chemotherapy and minimize its side-effects

K Krukiewicz, JK Zak - Materials Science and Engineering: C, 2016‏ - Elsevier
Since the majority of anticancer pharmacological agents affect not only cancer tissue but
also normal cells, chemotherapy is usually accompanied with severe side effects. Regional …

Influence of the structural orientation on the mechanical properties of selective laser melted Ti6Al4V open-porous scaffolds

V Weißmann, R Bader, H Hansmann, N Laufer - Materials & Design, 2016‏ - Elsevier
In order to reduce the implant stiffness, open-porous designs in two geometrical dimensions
were investigated (twisted design). Scaffolds were fabricated by an SLM process using …

Sol-gel deposition of hydroxyapatite coatings on porous titanium for biomedical applications

C Domínguez-Trujillo, E Peón, E Chicardi… - Surface and Coatings …, 2018‏ - Elsevier
The stress shielding and the poor osseointegration in titanium implants are still problems to
be resolved. In this context, this work proposes a balanced solution. Titanium samples were …

Fabrication of porous TiZrNbTa high-entropy alloys/Ti composite with high strength and low Young's modulus using a novel MgO space holder

T **ang, J Chen, W Bao, S Zhong, P Du… - Journal of Materials …, 2023‏ - Elsevier
Stress shielding is caused by the mismatch of stiffness between bone and implant materials,
which may give rise to bone resorption and loosening, thereby causing implantation failure …

[HTML][HTML] Electropolymerized polypyrrole silver nanocomposite coatings on porous Ti substrates with enhanced corrosion and antibacterial behavior for biomedical …

C García-Cabezón, V Godinho… - Materials Today …, 2023‏ - Elsevier
This work proposes an innovative strategy that combines two well-known easy and
economical preparation techniques: powder metallurgy based space-holder (SH) technique …

Porous titanium for biomedical applications: Evaluation of the conventional powder metallurgy frontier and space-holder technique

S Lascano, C Arévalo, I Montealegre-Melendez… - Applied sciences, 2019‏ - mdpi.com
Titanium and its alloys are reference materials in biomedical applications because of their
desirable properties. However, one of the most important concerns in long-term prostheses …

Designing bioactive porous titanium interfaces to balance mechanical properties and in vitro cells behavior towards increased osseointegration

A Civantos, C Domínguez, RJ Pino, G Setti… - Surface and Coatings …, 2019‏ - Elsevier
Titanium implant failures are mainly related to stress shielding phenomenon and the poor
cell interaction with host bone tissue. The development of bioactive and biomimetic Ti …

[HTML][HTML] Findings and perspectives of β-Ti alloys with biomedical applications: Exploring beyond biomechanical and biofunctional behaviour

AA Elhadad, L Romero-Resendiz, MC Rossi… - Journal of Materials …, 2024‏ - Elsevier
Early implant failure and bone resorption may occur in load-bearing conditions as a result of
stress shielding brought on by a mismatch in the bone-Ti-implant modulus. A review with a …