Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

The global obesity epidemic is well established, with increases in obesity prevalence for
most countries since the 1980s. Obesity contributes directly to incident cardiovascular risk …

Background Obesity is a chronic disease that results in substantial global morbidity and
mortality. The efficacy and safety of tirzepatide, a novel glucose-dependent insulinotropic …

Enormous progress has been made in the last half-century in the management of diseases
closely integrated with excess body weight, such as hypertension, adult-onset diabetes and …

Aims This report from the European Society of Cardiology (ESC) Atlas Project updates and
expands upon the widely cited 2019 report in presenting cardiovascular disease (CVD) …

The exclusion of other chronic liver diseases including “excess” alcohol intake has until now
been necessary to establish a diagnosis of metabolic dysfunction-associated fatty liver …

Adipose tissue, colloquially known as" fat," is an extraordinarily flexible and heterogeneous
organ. While historically viewed as a passive site for energy storage, we now appreciate that …

Aims The expression of GADD153 (growth arrest and DNA damage-inducible gene 153), an
apoptosis-regulated gene, increases during endoplasmic reticulum (ER) stress. How …

Surveys and registries are needed to verify that real-life daily practice is in kee** with what
is recommended in the guidelines, thus completing the loop between clinical research …

Objectives To identify data availability, gaps, and patterns for population level prevalence of
loneliness globally, to summarise prevalence estimates within World Health Organization …