Gut microbiota regulation of T cells during inflammation and autoimmunity

EM Brown, DJ Kenny, RJ Xavier - Annual review of immunology, 2019 - annualreviews.org
The intestinal microbiota plays a crucial role in influencing the development of host
immunity, and in turn the immune system also acts to regulate the microbiota through …

Neutrophils: from IBD to the gut microbiota

C Danne, J Skerniskyte, B Marteyn… - Nature Reviews …, 2024 - nature.com
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract that results from dysfunction in innate and/or adaptive immune responses. Impaired …

Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response

X Gao, Q Cao, Y Cheng, D Zhao… - Proceedings of the …, 2018 - National Acad Sciences
Chronic stress is known to promote inflammatory bowel disease (IBD), but the underlying
mechanism remains largely unresolved. Here, we found chronic stress to sensitize mice to …

A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers

MK Takahashi, X Tan, AJ Dy, D Braff, RT Akana… - Nature …, 2018 - nature.com
There is a need for large-scale, longitudinal studies to determine the mechanisms by which
the gut microbiome and its interactions with the host affect human health and disease …

Human gut microbiota stimulate defined innate immune responses that vary from phylum to strain

MP Spindler, S Siu, I Mogno, Z Li, C Yang… - Cell host & …, 2022 - cell.com
The potential of commensal bacteria to modulate host immunity remains largely
uncharacterized, largely due to the vast number of strains that comprise the human gut …

[HTML][HTML] Rapid transcriptional and metabolic adaptation of intestinal microbes to host immune activation

S Becattini, MT Sorbara, SG Kim, EL Littmann… - Cell Host & Microbe, 2021 - cell.com
The gut microbiota produces metabolites that regulate host immunity, thereby impacting
disease resistance and susceptibility. The extent to which commensal bacteria reciprocally …

Metatranscriptomics for the human microbiome and microbial community functional profiling

Y Zhang, KN Thompson, T Branck, Y Yan… - Annual Review of …, 2021 - annualreviews.org
Shotgun metatranscriptomics (MTX) is an increasingly practical way to survey microbial
community gene function and regulation at scale. This review begins by summarizing the …

Metagenomic and metatranscriptomic analysis of saliva reveals disease-associated microbiota in patients with periodontitis and dental caries

D Belstrøm, F Constancias, Y Liu, L Yang… - NPJ biofilms and …, 2017 - nature.com
The taxonomic composition of the salivary microbiota has been reported to differentiate
between oral health and disease. However, information on bacterial activity and gene …

Mucolytic bacteria license pathobionts to acquire host-derived nutrients during dietary nutrient restriction

K Sugihara, S Kitamoto, P Saraithong… - Cell reports, 2022 - cell.com
Pathobionts employ unique metabolic adaptation mechanisms to maximize their growth in
disease conditions. Adherent-invasive Escherichia coli (AIEC), a pathobiont enriched in the …

[HTML][HTML] Flos Abelmoschus manihot extract attenuates DSS-induced colitis by regulating gut microbiota and Th17/Treg balance

W Zhang, C Cheng, Q Han, Y Chen, J Guo… - Biomedicine & …, 2019 - Elsevier
Flos Abelmoschus manihot is widely used as traditional drug in China. Abelmoschus
manihot (AM) extracted from Flos Abelmoschus manihot that has been applied for treating …