Second-generation antipsychotics (SGAs) are the cornerstone of treatment for schizophrenia
because of their high clinical efficacy. However, SGA treatment is associated with severe …

Objective To quantify the risk of hip fracture, thromboembolism, stroke, myocardial infarction,
pneumonia and sudden cardiac death associated with exposure to antipsychotics. Methods …

Importance The Patient Protection and Affordable Care Act of 2010 brought attention to
adverse drug events in national patient safety efforts. Updated, detailed, nationally …

The objective of this study was to assess international trends in antipsychotic use, using a
standardised methodology. A repeated cross-sectional design was applied to data extracts …

Objectives For many research cohorts, it is not practical to provide a “gold‐standard” mental
health diagnosis. It is therefore important for mental health research that potential alternative …

Background Acutely occurring, life-threatening side-effects of antipsychotic drugs might
contribute to the reduced life expectancy observed in patients with severe mental disorders …

Background Global 12-month psychosis prevalence is estimated at roughly 0.4%, although
prevalence of antipsychotic use in the US is estimated at roughly 1.7%. Antipsychotics are …

Objective: To examine trends in prescribing psychotropic medications to children and
adolescents in Australian primary care from 2011 to 2018. Method: A retrospective cohort …

Alternatives to traditional categorical diagnoses have been proposed to improve the validity
and utility of psychiatric nosology. This paper continues the companion review of an …

The study included adults with 3 or more months of lifetime antipsychotic exposure and 1 or
more psychiatric disorder. Based on clinician observation and assessment, patients were …