Diagnosis and management of multiple myeloma: a review

AJ Cowan, DJ Green, M Kwok, S Lee, DG Coffey… - Jama, 2022 - jamanetwork.com
Importance Multiple myeloma is a hematologic malignancy characterized by presence of
abnormal clonal plasma cells in the bone marrow, with potential for uncontrolled growth …

International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders

J Hillengass, S Usmani, SV Rajkumar… - The lancet …, 2019 - thelancet.com
Recent advances in the treatment of multiple myeloma have increased the need for accurate
diagnosis of the disease. The detection of bone and bone marrow lesions is crucial in the …

Multiple myeloma: 2022 update on diagnosis, risk stratification, and management

SV Rajkumar - American journal of hematology, 2022 - Wiley Online Library
Abstract Disease Overview Multiple myeloma accounts for approximately 10% of
hematologic malignancies. Diagnosis The diagnosis requires≥ 10% clonal bone marrow …

[PDF][PDF] Advances in Understanding and Managing Multiple Myeloma: A Comprehensive Review

I Karunarathna, K Gunawardana, P Aluthge… - 2024 - researchgate.net
Multiple myeloma (MM) is a clonal plasma cell disorder marked by the production of
monoclonal immunoglobulins, leading to various end-organ damages including …

International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma

SV Rajkumar, MA Dimopoulos, A Palumbo… - The lancet …, 2014 - thelancet.com
Summary This International Myeloma Working Group consensus updates the disease
definition of multiple myeloma to include validated biomarkers in addition to existing …

Targeting B cell maturation antigen (BCMA) in multiple myeloma: potential uses of BCMA-based immunotherapy

SF Cho, KC Anderson, YT Tai - Frontiers in immunology, 2018 - frontiersin.org
The approval of the first two monoclonal antibodies targeting CD38 (daratumumab) and
SLAMF7 (elotuzumab) in late 2015 for treating relapsed and refractory multiple myeloma …

Multiple myeloma: diagnosis and treatment

SV Rajkumar, S Kumar - Mayo Clinic Proceedings, 2016 - Elsevier
The diagnosis and treatment of multiple myeloma has changed dramatically in the past
decade. The disease definition has been updated to include highly specific biomarkers in …

Multiple myeloma: 2016 update on diagnosis, risk‐stratification, and management

SV Rajkumar - American journal of hematology, 2016 - Wiley Online Library
Multiple myeloma accounts for approximately 10% of hematologic malignancies. The
diagnosis requires≥ 10% clonal bone marrow plasma cells or a biopsy proven …

The proteasome and proteasome inhibitors in multiple myeloma

S Gandolfi, JP Laubach, T Hideshima… - Cancer and Metastasis …, 2017 - Springer
Proteasome inhibitors are one of the most important classes of agents to have emerged for
the treatment of multiple myeloma in the past two decades, and now form one of the …

Multiple myeloma: available therapies and causes of drug resistance

V Pinto, R Bergantim, HR Caires, H Seca… - Cancers, 2020 - mdpi.com
Multiple myeloma (MM) is the second most common blood cancer. Treatments for MM
include corticosteroids, alkylating agents, anthracyclines, proteasome inhibitors …