Agent-based models of malaria transmission: a systematic review
Background Much of the extensive research regarding transmission of malaria is
underpinned by mathematical modelling. Compartmental models, which focus on …
underpinned by mathematical modelling. Compartmental models, which focus on …
Pathogenicity and virulence of malaria: Sticky problems and tricky solutions
IS Walker, SJ Rogerson - Virulence, 2023 - Taylor & Francis
Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …
each year, concentrated in Africa and in young children, but much of the world's population …
Plasmodium falciparum is evolving to escape malaria rapid diagnostic tests in Ethiopia
SM Feleke, EN Reichert, H Mohammed… - Nature …, 2021 - nature.com
In Africa, most rapid diagnostic tests (RDTs) for falciparum malaria recognize histidine-rich
protein 2 antigen. Plasmodium falciparum parasites lacking histidine-rich protein 2 (pfhrp2) …
protein 2 antigen. Plasmodium falciparum parasites lacking histidine-rich protein 2 (pfhrp2) …
High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion ty** by digital PCR to monitor malaria rapid diagnostic test efficacy
Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich
Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false …
Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false …
Systematic review of the status of pfhrp2 and pfhrp3 gene deletion, approaches and methods used for its estimation and reporting in Plasmodium falciparum …
BB Agaba, A Yeka, S Nsobya, E Arinaitwe… - Malaria journal, 2019 - Springer
Background Malaria rapid diagnostic tests based on histidine-rich protein-2 have played a
vital role in improving malaria case management and surveillance particularly in Africa …
vital role in improving malaria case management and surveillance particularly in Africa …
Genetic diversity and deletion of Plasmodium falciparum histidine-rich protein 2 and 3: a threat to diagnosis of P. falciparum malaria
Background PfHRP2-based rapid diagnostic tests (RDTs), based on the recognition of the
Plasmodium falciparum histidine-rich protein 2, are currently the most used tests in malaria …
Plasmodium falciparum histidine-rich protein 2, are currently the most used tests in malaria …
Genetic diversity and drug resistance surveillance of Plasmodium falciparum for malaria elimination: is there an ideal tool for resource-limited sub-Saharan Africa?
The intensification of malaria control interventions has resulted in its global decline, but it
remains a significant public health burden especially in sub-Saharan Africa (sSA) …
remains a significant public health burden especially in sub-Saharan Africa (sSA) …
Factors affecting the performance of HRP2-based malaria rapid diagnostic tests
The recent COVID-19 pandemic has profoundly impacted global malaria elimination
programs, resulting in a sharp increase in malaria morbidity and mortality. To reduce this …
programs, resulting in a sharp increase in malaria morbidity and mortality. To reduce this …
Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia: implication for malaria diagnosis
GS Alemayehu, K Blackburn, K Lopez… - Malaria journal, 2021 - Springer
Abstract Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2 (HRP2)
are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the …
are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the …
False-negative malaria rapid diagnostic test results and their impact on community-based malaria surveys in sub-Saharan Africa
Surveillance and diagnosis of Plasmodium falciparum malaria relies predominantly on rapid
diagnostic tests (RDT). However, false-negative (FN) RDT results are known to occur for a …
diagnostic tests (RDT). However, false-negative (FN) RDT results are known to occur for a …