Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Background Much of the extensive research regarding transmission of malaria is
underpinned by mathematical modelling. Compartmental models, which focus on …

In Africa, most rapid diagnostic tests (RDTs) for falciparum malaria recognize histidine-rich
protein 2 antigen. Plasmodium falciparum parasites lacking histidine-rich protein 2 (pfhrp2) …

Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich
Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false …

The recent COVID-19 pandemic has profoundly impacted global malaria elimination
programs, resulting in a sharp increase in malaria morbidity and mortality. To reduce this …

Surveillance and diagnosis of Plasmodium falciparum malaria relies predominantly on rapid
diagnostic tests (RDT). However, false-negative (FN) RDT results are known to occur for a …

The intensification of malaria control interventions has resulted in its global decline, but it
remains a significant public health burden especially in sub-Saharan Africa (sSA) …

Background The usefulness of histidine-rich protein-2/3 (HRP2/3)-based rapid diagnostic
tests of malaria due to Plasmodium falciparum has been threatened by the appearance of …

Background Malaria rapid diagnostic tests based on histidine-rich protein-2 have played a
vital role in improving malaria case management and surveillance particularly in Africa …

Artemether–lumefantrine (AL) and artesunate–amodiaquine (AS-AQ) are the most
commonly used artemisinin-based combination therapies (ACT) for treatment of …