[HTML][HTML] Vascular cognitive impairment (VCI)
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …
Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease
Therapies targeting late events in Alzheimer's disease (AD), including aggregation of
amyloid beta (Aβ) and hyperphosphorylated tau, have largely failed, probably because they …
amyloid beta (Aβ) and hyperphosphorylated tau, have largely failed, probably because they …
The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids
W **ao, J Su, X Gao, H Yang, R Weng, W Ni, Y Gu - Microbiome, 2022 - Springer
Background Chronic cerebral hypoperfusion (CCH) underlies secondary brain injury
following certain metabolic disorders and central nervous system (CNS) diseases …
following certain metabolic disorders and central nervous system (CNS) diseases …
Brain microvascular pericytes in vascular cognitive impairment and dementia
Pericytes are unique, multi-functional mural cells localized at the abluminal side of the
perivascular space in microvessels. Originally discovered in 19th century, pericytes had …
perivascular space in microvessels. Originally discovered in 19th century, pericytes had …
Alzheimer's disease: the link between amyloid-β and neurovascular dysfunction
While prevailing evidence supports that the amyloid cascade hypothesis is a key component
of Alzheimer's disease (AD) pathology, many recent studies indicate that the vascular …
of Alzheimer's disease (AD) pathology, many recent studies indicate that the vascular …
[HTML][HTML] Can exercise training teach us how to treat Alzheimer's disease?
AM Huuha, CS Norevik, JBN Moreira… - Ageing research …, 2022 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia and there is currently no
cure. Novel approaches to treat AD and curb the rapidly increasing worldwide prevalence …
cure. Novel approaches to treat AD and curb the rapidly increasing worldwide prevalence …
Primary hypothyroidism and Alzheimer's Disease: a tale of two
Hypothyroidism (HPT) HPT could be a risk factor for the development and progression of
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …
Intranasal insulin modulates cerebrospinal fluid markers of neuroinflammation in mild cognitive impairment and Alzheimer's disease: A randomized trial
Intranasal insulin (INI) has shown promise as a treatment for Alzheimer's disease (AD) in
pilot clinical trials. In a recent phase 2 trial, participants with mild cognitive impairment (MCI) …
pilot clinical trials. In a recent phase 2 trial, participants with mild cognitive impairment (MCI) …
Cerebral small vessel disease and Alzheimer's disease: a review
HW Kim, J Hong, JC Jeon - Frontiers in Neurology, 2020 - frontiersin.org
Alzheimer's disease (AD) is the most common cause of dementia. Despite this, clear
pathophysiology for AD has not been confirmed, and effective treatments are still not …
pathophysiology for AD has not been confirmed, and effective treatments are still not …
Association of intensive vs standard blood pressure control with cerebral blood flow: secondary analysis of the SPRINT MIND randomized clinical trial
Importance Antihypertensive treatments benefit cerebrovascular health and cognitive
function in patients with hypertension, but it is uncertain whether an intensive blood pressure …
function in patients with hypertension, but it is uncertain whether an intensive blood pressure …