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Pathogenicity and virulence of Aspergillus fumigatus
Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …
cause of morbidity and mortality globally. Compromised lung defences arising from …
Antifungal resistance, combinations and pipeline: oh my!
Invasive fungal infections are a strong contributor to healthcare costs, morbidity and
mortality, especially amongst hospitalized patients. Historically, Candida was responsible for …
mortality, especially amongst hospitalized patients. Historically, Candida was responsible for …
Multi-omics reveals the increased biofilm formation of Salmonella Typhimurium M3 by the induction of tetracycline at sub-inhibitory concentrations
L Yuan, L Fan, H Dai, G He, X Zheng, S Rao… - Science of the Total …, 2023 - Elsevier
Exposure to sub-inhibitory concentrations (sub-MICs) of antibiotics could induce the biofilm
formation of microorganisms, but its underlying mechanisms still remain elusive. In the …
formation of microorganisms, but its underlying mechanisms still remain elusive. In the …
Unsaturated fatty acid perturbation combats emerging triazole antifungal resistance in the human fungal pathogen Aspergillus fumigatus
C Gutierrez-Perez, C Puerner, JT Jones, S Vellanki… - Mbio, 2024 - journals.asm.org
Contemporary antifungal therapies utilized to treat filamentous fungal infections are inhibited
by intrinsic and emerging drug resistance. Consequently, there is an urgent need to develop …
by intrinsic and emerging drug resistance. Consequently, there is an urgent need to develop …
Filamentous fungal biofilms: Conserved and unique aspects of extracellular matrix composition, mechanisms of drug resistance and regulatory networks in Aspergillus …
The filamentous fungus Aspergillus fumigatus is an ubiquitous mold that can cause invasive
pulmonary infections in immunocompromised patients. Within the lung, A. fumigatus forms …
pulmonary infections in immunocompromised patients. Within the lung, A. fumigatus forms …
Amino sugars influence Aspergillus fumigatus cell wall polysaccharide biosynthesis, and biofilm formation through interfering galactosaminogalactan deacetylation
R He, P Wei, AS Odiba, L Gao, S Usman, X Gong… - Carbohydrate …, 2024 - Elsevier
Aspergillus fumigatus is a ubiquitous fungal pathogen responsible for a significant number
of deaths annually due to invasive aspergillosis infection. While the utilization of diverse …
of deaths annually due to invasive aspergillosis infection. While the utilization of diverse …
The heat shock transcription factor HsfA plays a role in membrane lipids biosynthesis connecting thermotolerance and unsaturated fatty acid metabolism in Aspergillus …
Thermotolerance is a remarkable virulence attribute of Aspergillus fumigatus, but the
consequences of heat shock (HS) to the cell membrane of this fungus are unknown …
consequences of heat shock (HS) to the cell membrane of this fungus are unknown …
Recent developments in Aspergillus fumigatus research: diversity, drugs, and disease
N Kordana, A Johnson, K Quinn, JJ Obar… - Microbiology and …, 2025 - journals.asm.org
Advances in modern medical therapies for many previously intractable human diseases
have improved patient outcomes. However, successful disease treatment outcomes are …
have improved patient outcomes. However, successful disease treatment outcomes are …
Assessing the intracellular primary metabolic profile of Trichoderma reesei and Aspergillus niger grown on different carbon sources
Trichoderma reesei and Aspergillus niger are efficient biological platforms for the production
of various industrial products, including cellulases and organic acids. Nevertheless, despite …
of various industrial products, including cellulases and organic acids. Nevertheless, despite …