The purpose of this essay is to explore a mechanism underlying a central clinical paradox:
individuals with a wide range of different illnesses are often characterized by strikingly …

When the kidney is subjected to acute increases in blood pressure (BP), renal blood flow
(RBF) and glomerular filtration rate (GFR) are observed to remain relatively constant. Two …

According to classical concepts of physiologic control, healthy systems are self-regulated to
reduce variability and maintain physiologic constancy. Contrary to the predictions of …

To test the hypothesis that spontaneous changes in cerebral blood flow are primarily
induced by changes in arterial pressure and that cerebral autoregulation is a frequency …

Aims to provide an introduction to some key aspects of non-linear dynamics and outline their
applications to physiology and medicine. How proportionality and individual components of …

Pathologic states are associated with a loss of dynamical complexity. Therefore, therapeutic
interventions that increase physiologic complexity may enhance health status. Using …

The kinetic attributes of the afferent arteriole myogenic response were investigated using the
in vitro perfused hydronephrotic rat kidney. Equations describing the time course for …

Autoregulation of renal blood flow (RBF) is caused by the myogenic response (MR),
tubuloglomerular feedback (TGF), and a third regulatory mechanism that is independent of …

We evaluate the possibility that the 1/f fluctuations observed in many biological time series
result simply from the fact that biological processes have many inputs with differing time …

The kidney displays highly efficient autoregulation so that under steady-state conditions
renal blood flow (RBF) is independent of blood pressure over a wide range of pressure …