Caveolae as organizers of pharmacologically relevant signal transduction molecules
Caveolae, a subset of membrane (lipid) rafts, are flask-like invaginations of the plasma
membrane that contain caveolin proteins, which serve as organizing centers for cellular …
membrane that contain caveolin proteins, which serve as organizing centers for cellular …
The evolving role of lipid rafts and caveolae in G protein‐coupled receptor signaling: implications for molecular pharmacology
The many components of G‐protein‐coupled receptor (GPCR) signal transduction provide
cells with numerous combinations with which to customize their responses to hormones …
cells with numerous combinations with which to customize their responses to hormones …
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice
M Drab, P Verkade, M Elger, M Kasper, M Lohn… - science, 2001 - science.org
Caveolae are plasma membrane invaginations that may play an important role in numerous
cellular processes including transport, signaling, and tumor suppression. By targeted …
cellular processes including transport, signaling, and tumor suppression. By targeted …
Localization of cardiac L-type Ca2+ channels to a caveolar macromolecular signaling complex is required for β2-adrenergic regulation
RC Balijepalli, JD Foell, DD Hall… - Proceedings of the …, 2006 - National Acad Sciences
L-type Ca2+ channels play a critical role in regulating Ca2+-dependent signaling in cardiac
myocytes, including excitation-contraction coupling; however, the subcellular localization of …
myocytes, including excitation-contraction coupling; however, the subcellular localization of …
Caveolae and caveolins in the cardiovascular system
JP Gratton, P Bernatchez, WC Sessa - Circulation research, 2004 - Am Heart Assoc
Caveolae and the caveolae coat proteins, caveolins, are putatively implicated in many
cellular processes, including transcytosis of macromolecules, cholesterol transport, and …
cellular processes, including transcytosis of macromolecules, cholesterol transport, and …
Sphingolipids in mammalian cell signalling
J Ohanian, V Ohanian - Cellular and Molecular Life Sciences CMLS, 2001 - Springer
Sphingolipids and their metabolites, ceramide, sphingosine and sphingosine-1-phosphate,
are involved in a variety of cellular processes including differentiation, cellular senescence …
are involved in a variety of cellular processes including differentiation, cellular senescence …
ANO1, CaV1.2, and IP3R form a localized unit of EC-coupling in mouse pulmonary arterial smooth muscle
Pulmonary arterial (PA) smooth muscle cells (PASMC) generate vascular tone in response
to agonists coupled to Gq-protein receptor signaling. Such agonists stimulate oscillating …
to agonists coupled to Gq-protein receptor signaling. Such agonists stimulate oscillating …
Invited review: mechanisms of calcium handling in smooth muscles
KM Sanders - Journal of applied physiology, 2001 - journals.physiology.org
The concentration of cytoplasmic Ca2+ regulates the contractile state of smooth muscle cells
and tissues. Elevations in global cytoplasmic Ca2+ resulting in contraction are …
and tissues. Elevations in global cytoplasmic Ca2+ resulting in contraction are …
Fatal Cardiac Arrhythmia and Long-QT Syndrome in a New Form of Congenital Generalized Lipodystrophy with Muscle Rippling (CGL4) Due to PTRF-CAVIN …
We investigated eight families with a novel subtype of congenital generalized lipodystrophy
(CGL4) of whom five members had died from sudden cardiac death during their teenage …
(CGL4) of whom five members had died from sudden cardiac death during their teenage …
Invited Review: Arteriolar smooth muscle mechanotransduction: Ca2+ signaling pathways underlying myogenic reactivity
MA Hill, H Zou, SJ Potocnik… - Journal of applied …, 2001 - journals.physiology.org
The smooth muscle of arterioles responds to an increase in intraluminal pressure with
vasoconstriction and with vasodilation when pressure is decreased. Such myogenic …
vasoconstriction and with vasodilation when pressure is decreased. Such myogenic …