Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

Importance of genetic diversity assessment in crop plants and its recent advances: an overview of its analytical perspectives

M Govindaraj, M Vetriventhan… - Genetics research …, 2015 - Wiley Online Library
The importance of plant genetic diversity (PGD) is now being recognized as a specific area
since exploding population with urbanization and decreasing cultivable lands are the critical …

Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment

J Rhodes, A Abdolrasouli, K Dunne, TR Sewell… - Nature …, 2022 - nature.com
Infections caused by the fungal pathogen Aspergillus fumigatus are increasingly resistant to
first-line azole antifungal drugs. However, despite its clinical importance, little is known …

[HTML][HTML] Population genomics of post-glacial western Eurasia

ME Allentoft, M Sikora, A Refoyo-Martínez… - Nature, 2024 - nature.com
Western Eurasia witnessed several large-scale human migrations during the Holocene,,,–.
Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced …

[HTML][HTML] The UK Biobank resource with deep phenoty** and genomic data

C Bycroft, C Freeman, D Petkova, G Band, LT Elliott… - Nature, 2018 - nature.com
The UK Biobank project is a prospective cohort study with deep genetic and phenotypic data
collected on approximately 500,000 individuals from across the United Kingdom, aged …

Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations

W Barrie, Y Yang, EK Irving-Pease, KE Attfield… - Nature, 2024 - nature.com
Multiple sclerosis (MS) is a neuro-inflammatory and neurodegenerative disease that is most
prevalent in Northern Europe. Although it is known that inherited risk for MS is located within …

Accurate, scalable and integrative haplotype estimation

O Delaneau, JF Zagury, MR Robinson… - Nature …, 2019 - nature.com
The number of human genomes being genotyped or sequenced increases exponentially
and efficient haplotype estimation methods able to handle this amount of data are now …

Durum wheat genome highlights past domestication signatures and future improvement targets

M Maccaferri, NS Harris, SO Twardziok, RK Pasam… - Nature …, 2019 - nature.com
The domestication of wild emmer wheat led to the selection of modern durum wheat, grown
mainly for pasta production. We describe the 10.45 gigabase (Gb) assembly of the genome …

[KNIHA][B] Who we are and how we got here: Ancient DNA and the new science of the human past

D Reich - 2018 - books.google.com
The past few years have witnessed a revolution in our ability to obtain DNA from ancient
humans. This important new data has added to our knowledge from archaeology and …

Genome-wide genetic data on~ 500,000 UK Biobank participants

C Bycroft, C Freeman, D Petkova, G Band, LT Elliott… - BioRxiv, 2017 - biorxiv.org
The UK Biobank project is a large prospective cohort study of~ 500,000 individuals from
across the United Kingdom, aged between 40-69 at recruitment. A rich variety of phenotypic …