Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Tigecycline is one of the last-resort antibiotics to treat complicated infections caused by both
multidrug-resistant Gram-negative and Gram-positive bacteria. Tigecycline resistance has …

Tetracyclines possess many properties considered ideal for antibiotic drugs, including
activity against Gram-positive and-negative pathogens, proven clinical safety, acceptable …

The global emergence of multidrug-resistant Gram-negative bacteria is a growing threat to
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …

Multidrug resistance is quite common among non-fermenting Gram-negative rods, in
particular among clinically relevant species including Pseudomonas aeruginosa and …

Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

Acinetobacter baumannii has emerged as a highly troublesome pathogen for many
institutions globally. As a consequence of its immense ability to acquire or upregulate …

Drug efflux pumps play a key role in drug resistance and also serve other functions in
bacteria. There has been a growing list of multidrug and drug-specific efflux pumps …

The first decade of the 20th century witnessed a surge in the incidence of infections due to
several highly antimicrobial-resistant bacteria in hospitals worldwide. Acinetobacter …