Overwhelming evidence exists that lifelong exercise is associated with a longer health span,
delaying the onset of 40 chronic conditions/diseases. What is beginning to be learned is the …

Standardized animal models represent one of the most valuable tools available to
understand the mechanism underlying the metabolic syndrome (MetS) and to seek for new …

An important role for liver in the regulation of adipose tissue thermogenesis upon cold
exposure has been suggested; however, the underlying mechanisms remain incompletely …

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been reported to improve insulin
sensitivity and glucose homeostasis in animal models of insulin resistance, but the involved …

The activation of the bradykinin type 2 receptor is intricately involved in acute post-ischemic
inflammatory responses. However, its precise role in different stages of ischemic injury …

Adult skeletal muscle fibres are classified as type 1, 2A, 2X, and 2B. These classifications
are based on the expression of the dominant myosin heavy chain isoform. Muscle fibre …

Endurance is not only a key factor in many sports but endurance-related variables are also
associated with good health and low mortality. Twin and family studies suggest that several …

Obesity over‐activates the classical arm of the renin‐angiotensin system (RAS), impairing
skeletal muscle remodeling. We aimed to compare the effect of exercise training and …

Overactivation of the classical arm of the renin-angiotensin (Ang) system (RAS) occurs
during inflammation, oxidative stress and obesity-induced cardiomyopathy. The activation of …

Bradykinin (BK) promotes insulin sensitivity and glucose uptake in adipocytes and other cell
types. We demonstrated that in rat adipocytes BK enhances insulin-stimulated glucose …