Heat shock proteins (HSPs) based anti-cancer vaccines

DR Ciocca, N Cayado-Gutierrez… - Current molecular …, 2012 - ingentaconnect.com
The importance of HSPs themselves in antigen presentation and cross-presentation remains
controversial. Most studies agree that as part of their molecular chaperone function, HSPs …

Immunotherapy of head and neck cancer: current and future considerations

AD Rapidis, GT Wolf - Journal of oncology, 2009 - Wiley Online Library
Patients with head and neck squamous cell carcinoma (HNSCC) are at considerable risk for
death, with 5‐year relative survival rates of approximately 60%. The profound multifaceted …

An HPV-E6/E7 immunotherapy plus PD-1 checkpoint inhibition results in tumor regression and reduction in PD-L1 expression

AE Rice, YE Latchman, JP Balint, JH Lee… - Cancer gene …, 2015 - nature.com
We have investigated if immunotherapy against human papilloma virus (HPV) using a viral
gene delivery platform to immunize against HPV 16 genes E6 and E7 (Ad5 [E1-, E2b-] …

Recent advances in strategies for immunotherapy of human papillomavirus‐induced lesions

S Kanodia, DM Da Silva… - International journal of …, 2008 - Wiley Online Library
Human papillomavirus (HPV)‐induced lesions are distinct in that they have targetable
foreign antigens, the expression of which is necessary to maintain the cancerous phenotype …

[HTML][HTML] Identification and characterization of enhancer agonist human cytotoxic T-cell epitopes of the human papillomavirus type 16 (HPV16) E6/E7

KY Tsang, M Fantini, RI Fernando, C Palena, JM David… - Vaccine, 2017 - Elsevier
Human papillomavirus (HPV) is associated with the etiology of cervical carcinoma, head and
neck squamous cell carcinoma, and several other cancer types. Vaccines directed against …

Association of CTLA‐4, TNF alpha and IL 10 polymorphisms with susceptibility to hepatocellular carcinoma

J Wang, Z Wang, T Tan - Scandinavian Journal of Immunology, 2019 - Wiley Online Library
Our aim was to evaluate the association of genetic polymorphisms of immunoregulatory
molecules with susceptibility to hepatocellular carcinoma (HCC). The polymorphisms in …

REBACIN® as a noninvasive clinical intervention for high‐risk human papillomavirus persistent infection

Y Yang, YL Meng, SM Duan, SB Zhan… - … journal of cancer, 2019 - Wiley Online Library
The development of highly sensitive HPV‐genoty** tests has opened the possibility of
treating HPV‐infected women before high‐grade lesions appear. The lack of efficient …

High prevalence of human papillomavirus in esophageal squamous cell carcinoma: a study in paired samples

K Vaiphei, R Kochhar, S Bhardawaj… - Diseases of the …, 2013 - academic.oup.com
Esophageal squamous cell carcinoma (ESCC) is one of the common cancers with a poor
prognosis. Incidences of human papillomavirus (HPV) infection range from 0 to 67% in …

[HTML][HTML] Therapeutic vaccines for gastrointestinal cancers

OE Rahma, SN Khleif - Gastroenterology & hepatology, 2011 - ncbi.nlm.nih.gov
Despite progress in the management of gastrointestinal malignancies, these diseases
remain devastating maladies. Conventional treatment with chemotherapy and radiation is …

Therapeutic human papillomavirus vaccination

AE Albers, AM Kaufmann - Public Health Genomics, 2009 - karger.com
Despite impressive progress in prevention and therapy of premalignant and malignant
dysplasia the worldwide burden of cancer is relatively unchanged. Supplementation of the …