Platelet-rich plasma: a comparative and economical therapy for wound healing and tissue regeneration

R Verma, S Kumar, P Garg, YK Verma - Cell and Tissue Banking, 2023 - Springer
Rise in the incidences of chronic degenerative diseases with aging makes wound care a
socio-economic burden and unceasingly necessitates a novel, economical, and efficient …

Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents

XR Xu, GM Yousef, H Ni - Blood, The Journal of the American …, 2018 - ashpublications.org
Platelets have long been recognized as key players in hemostasis and thrombosis;
however, growing evidence suggests that they are also significantly involved in cancer, the …

Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond

XR Xu, D Zhang, BE Oswald, N Carrim… - Critical reviews in …, 2016 - Taylor & Francis
Platelets are small anucleate blood cells generated from megakaryocytes in the bone
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …

Platelets in hemostasis and thrombosis: Novel mechanisms of fibrinogen-independent platelet aggregation and fibronectin-mediated protein wave of hemostasis

Y Hou, N Carrim, Y Wang, RC Gallant… - Journal of …, 2015 - pmc.ncbi.nlm.nih.gov
Platelets are small anucleate cells generated from megakaryocytes in the bone marrow.
Although platelet generation, maturation, and clearance are still not fully understood …

Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapies

XR Xu, N Carrim, MAD Neves, T McKeown… - Thrombosis journal, 2016 - Springer
Platelets are central mediators of thrombosis and hemostasis. At the site of vascular injury,
platelet accumulation (ie adhesion and aggregation) constitutes the first wave of hemostasis …

Platelet transfusions improve hemostasis and survival in a substudy of the prospective, randomized PROPPR trial

JC Cardenas, X Zhang, EE Fox, BA Cotton… - Blood …, 2018 - ashpublications.org
Transfusing platelets during massive hemorrhage is debated because of a lack of high-
quality evidence concerning outcomes in trauma patients. The objective of this study was to …

Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude

M Li, X Tang, Z Liao, C Shen, R Cheng… - Blood, The Journal …, 2022 - ashpublications.org
Studies have shown significantly increased thromboembolic events at high altitude. We
recently reported that transferrin could potentiate blood coagulation, but the underlying …

Plasma fibronectin supports hemostasis and regulates thrombosis

Y Wang, A Reheman, CM Spring, J Kalantari… - The Journal of clinical …, 2014 - jci.org
Plasma fibronectin (pFn) has long been suspected to be involved in hemostasis; however,
direct evidence has been lacking. Here, we demonstrated that pFn is vital to control bleeding …

Crosstalk between platelets and microbial pathogens

C Li, J Li, H Ni - Frontiers in immunology, 2020 - frontiersin.org
Platelets, small anucleate cells circulating in the blood, are critical mediators in haemostasis
and thrombosis. Interestingly, recent studies demonstrated that platelets contain both pro …

Regulation of platelet function and thrombosis by omega-3 and omega-6 polyunsaturated fatty acids

R Adili, M Hawley, M Holinstat - Prostaglandins & other lipid mediators, 2018 - Elsevier
Thrombosis is the most common underlying pathology responsible for morbidity and
mortality in cardiovascular disease (CVD). Platelet adhesion, activation, and aggregation …