Interplay between inflammation and thrombosis in cardiovascular pathology

K Stark, S Massberg - Nature Reviews Cardiology, 2021 - nature.com
Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

Neutrophil extracellular traps in immunity and disease

V Papayannopoulos - Nature Reviews Immunology, 2018 - nature.com
Neutrophils are innate immune phagocytes that have a central role in immune defence. Our
understanding of the role of neutrophils in pathogen clearance, immune regulation and …

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

BJ Barnes, JM Adrover, A Baxter-Stoltzfus… - Journal of Experimental …, 2020 - rupress.org
Disclosures: MR Looney reported" other" from Neutrolis outside the submitted work. RE
Schwartz is a Sponsored Advisory Board Member for Miromatrix Inc. JD Spicer reported …

[HTML][HTML] Neutrophil extracellular traps in COVID-19

Y Zuo, S Yalavarthi, H Shi, K Gockman, M Zuo… - JCI insight, 2020 - ncbi.nlm.nih.gov
In severe cases of coronavirus disease 2019 (COVID-19), viral pneumonia progresses to
respiratory failure. Neutrophil extracellular traps (NETs) are extracellular webs of chromatin …

The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications

JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing global pandemic has presented a health emergency of unprecedented …

[HTML][HTML] Large-scale multi-omic analysis of COVID-19 severity

KA Overmyer, E Shishkova, IJ Miller, J Balnis… - Cell systems, 2021 - cell.com
We performed RNA-seq and high-resolution mass spectrometry on 128 blood samples from
COVID-19-positive and COVID-19-negative patients with diverse disease severities and …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

A comparative study on the clinical features of coronavirus 2019 (COVID-19) pneumonia with other pneumonias

D Zhao, F Yao, L Wang, L Zheng, Y Gao… - Clinical infectious …, 2020 - academic.oup.com
Background A novel coronavirus (COVID-19) has raised world concern since it emerged in
Wuhan, China in December 2019. The infection may result in severe pneumonia with …

Histopathologic changes and SARS-CoV-2 immunostaining in the lung of a patient with COVID-19

H Zhang, P Zhou, Y Wei, H Yue, Y Wang… - Annals of internal …, 2020 - acpjournals.org
Background: Although many studies have demonstrated the epidemiologic characteristics of
SARS-CoV-2 disease (COVID-19), details of pathologic changes in the lung are still lacking …

[HTML][HTML] COVID-19 and the liver: little cause for concern

MN Bangash, J Patel, D Parekh - The lancet. Gastroenterology & …, 2020 - ncbi.nlm.nih.gov
The largest study on COVID-19 to date1 showed that the prevalence of elevated
aminotransferases and bilirubin in people faring worst was at least double that of others …