[HTML][HTML] Unusual structures and unknown roles of FeS clusters in metalloenzymes seen from a resonance Raman spectroscopic perspective
G Caserta, L Zuccarello, C Barbosa, CM Silveira… - Coordination Chemistry …, 2022 - Elsevier
The universe of known biological FeS clusters is constantly enlarging. Besides the
conventional, well described [2Fe–2S],[3Fe–4S] and cubane [4Fe–4S] clusters, novel …
conventional, well described [2Fe–2S],[3Fe–4S] and cubane [4Fe–4S] clusters, novel …
Outlining the complex pathway of mammalian Fe-S cluster biogenesis
N Maio, TA Rouault - Trends in biochemical sciences, 2020 - cell.com
Iron–sulfur (Fe-S) clusters (ISCs) are ubiquitous cofactors essential to numerous
fundamental cellular processes. Assembly of ISCs and their insertion into apoproteins …
fundamental cellular processes. Assembly of ISCs and their insertion into apoproteins …
Highly ordered and field-free 3D DNA nanostructure: the next generation of DNA nanomachine for rapid single-step sensing
P Zhang, J Jiang, R Yuan, Y Zhuo… - Journal of the American …, 2018 - ACS Publications
Herein, by directly using Watson–Crick base pairing, a highly ordered and field-free three-
dimensional (3D) DNA nanostructure is self-assembled by azobenzene (azo)-functionalized …
dimensional (3D) DNA nanostructure is self-assembled by azobenzene (azo)-functionalized …
Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism
DNA glycosylase MutY plays a critical role in suppression of mutations resulted from
oxidative damage, as highlighted by cancer-association of the human enzyme. MutY …
oxidative damage, as highlighted by cancer-association of the human enzyme. MutY …
Redox chemistry in the genome: emergence of the [4Fe4S] cofactor in repair and replication
JK Barton, RMB Silva, E O'Brien - Annual review of biochemistry, 2019 - annualreviews.org
Many DNA-processing enzymes have been shown to contain a [4Fe4S] cluster, a common
redox cofactor in biology. Using DNA electrochemistry, we find that binding of the DNA …
redox cofactor in biology. Using DNA electrochemistry, we find that binding of the DNA …
Impact of transient acquired hypermutability on the inter- and intra-species competitiveness of Pseudomonas aeruginosa
Once acquired, hypermutation is unrelenting, and in the long-term, leads to impaired fitness
due to its cumulative impact on the genome. This raises the question of why hypermutators …
due to its cumulative impact on the genome. This raises the question of why hypermutators …
Sensing DNA through DNA charge transport
DNA charge transport chemistry involves the migration of charge over long molecular
distances through the aromatic base pair stack within the DNA helix. This migration depends …
distances through the aromatic base pair stack within the DNA helix. This migration depends …
Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme
R Jain, WJ Rice, R Malik, RE Johnson… - Nature structural & …, 2019 - nature.com
DNA polymerase δ (Polδ) plays pivotal roles in eukaryotic DNA replication and repair. Polδ
is conserved from yeast to humans, and mutations in human Polδ have been implicated in …
is conserved from yeast to humans, and mutations in human Polδ have been implicated in …
The [4Fe4S] cluster of yeast DNA polymerase ε is redox active and can undergo DNA-mediated signaling
Many DNA replication and DNA repair enzymes have been found to carry [4Fe4S] clusters.
The major leading strand polymerase, DNA polymerase ε (Pol ε) from Saccharomyces …
The major leading strand polymerase, DNA polymerase ε (Pol ε) from Saccharomyces …
A combined Far-FTIR, FTIR Spectromicroscopy, and DFT Study of the Effect of DNA Binding on the [4Fe4S] Cluster Site in EndoIII
Endonuclease III (EndoIII) is a DNA glycosylase that contains the [4Fe4S] cluster, which is
essential for the protein to bind to damaged DNA in a process called base excision repair …
essential for the protein to bind to damaged DNA in a process called base excision repair …