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[HTML][HTML] Iron mediated toxicity and programmed cell death: A review and a re-examination of existing paradigms
Iron is an essential micronutrient that is problematic for biological systems since it is toxic as
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …
it generates free radicals by interconverting between ferrous (Fe 2+) and ferric (Fe 3+) forms …
[HTML][HTML] Copper metabolism and its role in diabetic complications: A review
D Jia, L Liu, W Liu, J Li, X Jiang, Y **n - Pharmacological Research, 2024 - Elsevier
Disturbances in copper (Cu) homeostasis have been observed in diabetes and associated
complications. Cu is an essential micronutrient that plays important roles in various …
complications. Cu is an essential micronutrient that plays important roles in various …
Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma
F Yao, J Peng, E Zhang, D Ji, Z Gao, Y Tang… - Cell Death & …, 2023 - nature.com
Glaucoma can result in retinal ganglion cell (RGC) death and permanently damaged vision.
Pathologically high intraocular pressure (ph-IOP) is the leading cause of damaged vision …
Pathologically high intraocular pressure (ph-IOP) is the leading cause of damaged vision …
The many “faces” of copper in medicine and treatment
A Hordyjewska, Ł Popiołek, J Kocot - Biometals, 2014 - Springer
Copper (Cu) is an essential microelement found in all living organisms with the unique
ability to adopt two different redox states—in the oxidized (Cu 2+) and reduced (Cu+). It is …
ability to adopt two different redox states—in the oxidized (Cu 2+) and reduced (Cu+). It is …
Senescence in the pathogenesis of age-related macular degeneration
J Blasiak - Cellular and Molecular Life Sciences, 2020 - Springer
Age-related macular degeneration (AMD) is a complex eye disease underlined by the death
of photoreceptors and degeneration of retinal pigment epithelium (RPE) and choriocapillaris …
of photoreceptors and degeneration of retinal pigment epithelium (RPE) and choriocapillaris …
Pyrene-Based Fluorescent Probe for “Off-on-Off” Sequential Detection of Cu2+ and CN− with HeLa Cells Imaging
M Shellaiah, P Venkatesan, N Thirumalaivasan, SP Wu… - Chemosensors, 2023 - mdpi.com
The novel pyrene-appended Schiff base probe L with aggregation-induced emissions (AIE)
relevant to an increase in water fractions (0–90%) is synthesized and applied in sequentially …
relevant to an increase in water fractions (0–90%) is synthesized and applied in sequentially …
[HTML][HTML] The age-related eye disease 2 study: micronutrients in the treatment of macular degeneration
A Gorusupudi, K Nelson, PS Bernstein - Advances in Nutrition, 2017 - Elsevier
Age-related macular degeneration (AMD) is one of the leading causes of vision loss in the
elderly. With an increasingly aged population worldwide, the need for the prevention of AMD …
elderly. With an increasingly aged population worldwide, the need for the prevention of AMD …
[HTML][HTML] Anthropogenic hyperactivity for natural resources increases heavy metals concentrations in the environment: Toxicity of healthy food and cancer risks …
DJ Machate - Journal of Trace Elements and Minerals, 2023 - Elsevier
Anthropogenic hyperactivities for natural resources cause increasing concentrations of
heavy metals and metalloids in the environment, which hazard human health. This review …
heavy metals and metalloids in the environment, which hazard human health. This review …
[HTML][HTML] Effects of copper exposure on oxidative stress, apoptosis, endoplasmic reticulum stress, autophagy and immune response in different tissues of Chinese …
W Feng, S Su, C Song, F Yu, J Zhou, J Li, R Jia, P Xu… - Antioxidants, 2022 - mdpi.com
High concentrations of copper (Cu2+) pose a great threat to aquatic animals. However, the
mechanisms underlying the response of crustaceans to Cu2+ exposure have not been well …
mechanisms underlying the response of crustaceans to Cu2+ exposure have not been well …
Temporal single-cell atlas of non-neuronal retinal cells reveals dynamic, coordinated multicellular responses to central nervous system injury
Non-neuronal cells are key to the complex cellular interplay that follows central nervous
system insult. To understand this interplay, we generated a single-cell atlas of immune, glial …
system insult. To understand this interplay, we generated a single-cell atlas of immune, glial …