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Mechanical state transitions in the regulation of tissue form and function
From embryonic development, postnatal growth and adult homeostasis to reparative and
disease states, cells and tissues undergo constant changes in genome activity, cell fate …
disease states, cells and tissues undergo constant changes in genome activity, cell fate …
Physics of microswimmers—single particle motion and collective behavior: a review
Locomotion and transport of microorganisms in fluids is an essential aspect of life. Search
for food, orientation toward light, spreading of off-spring, and the formation of colonies are …
for food, orientation toward light, spreading of off-spring, and the formation of colonies are …
Cell–cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion
O Ilina, PG Gritsenko, S Syga, J Lippoldt… - Nature cell …, 2020 - nature.com
Plasticity of cancer invasion and metastasis depends on the ability of cancer cells to switch
between collective and single-cell dissemination, controlled by cadherin-mediated cell–cell …
between collective and single-cell dissemination, controlled by cadherin-mediated cell–cell …
A fluid-to-solid jamming transition underlies vertebrate body axis elongation
Just as in clay moulding or glass blowing, physically sculpting biological structures requires
the constituent material to locally flow like a fluid while maintaining overall mechanical …
the constituent material to locally flow like a fluid while maintaining overall mechanical …
Motility-driven glass and jamming transitions in biological tissues
Cell motion inside dense tissues governs many biological processes, including embryonic
development and cancer metastasis, and recent experiments suggest that these tissues …
development and cancer metastasis, and recent experiments suggest that these tissues …
Unjamming and cell shape in the asthmatic airway epithelium
From coffee beans flowing in a chute to cells remodelling in a living tissue, a wide variety of
close-packed collective systems—both inert and living—have the potential to jam. The …
close-packed collective systems—both inert and living—have the potential to jam. The …
Self-enhanced mobility enables vortex pattern formation in living matter
Ranging from subcellular organelle biogenesis to embryo development, the formation of self-
organized structures is a hallmark of living systems. Whereas the emergence of ordered …
organized structures is a hallmark of living systems. Whereas the emergence of ordered …
A density-independent rigidity transition in biological tissues
Cell migration is important in many biological processes, including embryonic development,
cancer metastasis and wound healing. In these tissues, a cell's motion is often strongly …
cancer metastasis and wound healing. In these tissues, a cell's motion is often strongly …
Mechanisms and impact of altered tumour mechanics
H Mohammadi, E Sahai - Nature cell biology, 2018 - nature.com
The physical characteristics of tumours are intricately linked to the tumour phenotype and
difficulties during treatment. Many factors contribute to the increased stiffness of tumours; …
difficulties during treatment. Many factors contribute to the increased stiffness of tumours; …
Hydrodynamics of soft active matter
This review summarizes theoretical progress in the field of active matter, placing it in the
context of recent experiments. This approach offers a unified framework for the mechanical …
context of recent experiments. This approach offers a unified framework for the mechanical …