Recent advances in machine learning applications in metabolic engineering
Metabolic engineering encompasses several widely-used strategies, which currently hold a
high seat in the field of biotechnology when its potential is manifesting through a plethora of …
high seat in the field of biotechnology when its potential is manifesting through a plethora of …
[HTML][HTML] Unlocking the mitochondria for nanomedicine-based treatments: overcoming biological barriers, improving designs, and selecting verification techniques
C Pegoraro, I Domingo-Ortí, I Conejos-Sánchez… - Advanced Drug Delivery …, 2024 - Elsevier
Enhanced targeting approaches will support the treatment of diseases associated with
dysfunctional mitochondria, which play critical roles in energy generation and cell survival …
dysfunctional mitochondria, which play critical roles in energy generation and cell survival …
Gluconeogenesis flux in metabolic disease
A Shah, FE Wondisford - Annual Review of Nutrition, 2023 - annualreviews.org
Gluconeogenesis is a critical biosynthetic process that helps maintain whole-body glucose
homeostasis and becomes altered in certain medical diseases. We review gluconeogenic …
homeostasis and becomes altered in certain medical diseases. We review gluconeogenic …
Machine learning for the advancement of genome-scale metabolic modeling
Constraint-based modeling (CBM) has evolved as the core systems biology tool to map the
interrelations between genotype, phenotype, and external environment. The recent …
interrelations between genotype, phenotype, and external environment. The recent …
The detection of adulteration of olive oil with various vegetable oils–A case study using high-resolution 700 MHz NMR spectroscopy coupled with multivariate data …
Olive oil, being very salubrious, is one of the main ingredients of the Mediterranean diet.
However, high oil prices combined with high consumption have increasingly subjected olive …
However, high oil prices combined with high consumption have increasingly subjected olive …
Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis
Mammalian retinal metabolism favors aerobic glycolysis. However, the role of glycolytic
metabolism in retinal morphogenesis remains unknown. We report that aerobic glycolysis is …
metabolism in retinal morphogenesis remains unknown. We report that aerobic glycolysis is …
[HTML][HTML] Prospects of single-cell nuclear magnetic resonance spectroscopy with quantum sensors
Highlights•Nitrogen-vacancy (NV) centers in diamond are atom-sized quantum sensors.•NV
centers enable nuclear magnetic resonance (NMR) spectroscopy on the previously …
centers enable nuclear magnetic resonance (NMR) spectroscopy on the previously …
Plant life with and without oxygen: A metabolomics approach
VV Yemelyanov, RK Puzanskiy… - International Journal of …, 2023 - mdpi.com
Oxygen deficiency is an environmental challenge which affects plant growth, the
development and distribution in land and aquatic ecosystems, as well as crop yield losses …
development and distribution in land and aquatic ecosystems, as well as crop yield losses …
Enhancement of weak signals by applying a suppression method to high-intense methyl and methylene signals of lipids in NMR spectroscopy
U Singh, AH Emwas, M Jaremko - RSC advances, 2024 - pubs.rsc.org
Lipids play crucial roles in human biology, serving as energy stores, cell membranes,
hormone production, and signaling molecules. Accordingly, their study under lipidomics has …
hormone production, and signaling molecules. Accordingly, their study under lipidomics has …
Challenges and recent advances in quantitative mass spectrometry‐based metabolomics
N Ghafari, L Sleno - Analytical Science Advances, 2024 - Wiley Online Library
The field of metabolomics has gained tremendous interest in recent years. Whether the goal
is to discover biomarkers related to certain pathologies or to better understand the impact of …
is to discover biomarkers related to certain pathologies or to better understand the impact of …