Prefrontal cortex as a key node in arousal circuitry

GA Mashour, D Pal, EN Brown - Trends in neurosciences, 2022 - cell.com
The role of the prefrontal cortex (PFC) in the mechanism of consciousness is a matter of
active debate. Most theoretical and empirical investigations have focused on whether the …

Functional connectivity of the brain across rodents and humans

N Xu, TJ LaGrow, N Anumba, A Lee, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Resting-state functional magnetic resonance imaging (rs-fMRI), which measures the
spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, is …

Genetic and phylogenetic uncoupling of structure and function in human transmodal cortex

SL Valk, T Xu, C Paquola, B Park… - Nature …, 2022 - nature.com
Brain structure scaffolds intrinsic function, supporting cognition and ultimately behavioral
flexibility. However, it remains unclear how a static, genetically controlled architecture …

Whole-brain comparison of rodent and human brains using spatial transcriptomics

A Beauchamp, Y Yee, BC Darwin, A Raznahan… - Elife, 2022 - elifesciences.org
The ever-increasing use of mouse models in preclinical neuroscience research calls for an
improvement in the methods used to translate findings between mouse and human brains …

[책][B] In consciousness we trust: The cognitive neuroscience of subjective experience

H Lau - 2022 - books.google.com
In Consciousness We Trust is a synthesis of Hakwan Lau's 20-year research programme
exploring the neuroscience of consciousness. Discussing studies from his own laboratory …

Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging

H Zhang, J Li, Y Yu, J Ren, Q Liu, Z Bao, S Sun, X Liu… - Cell reports, 2023 - cell.com
The primate frontal lobe (FL) is sensitive to aging-related neurocognitive decline. However,
the aging-associated molecular mechanisms remain unclear. Here, using physiologically …

Optogenetic stimulation of anterior insular cortex neurons in male rats reveals causal mechanisms underlying suppression of the default mode network by the salience …

V Menon, D Cerri, B Lee, R Yuan, SH Lee… - Nature …, 2023 - nature.com
The salience network (SN) and default mode network (DMN) play a crucial role in cognitive
function. The SN, anchored in the anterior insular cortex (AI), has been hypothesized to …

A vocalization-processing network in marmosets

A Jafari, A Dureux, A Zanini, RS Menon, KM Gilbert… - Cell Reports, 2023 - cell.com
Vocalizations play an important role in the daily life of primates and likely form the basis of
human language. Functional imaging studies have demonstrated that listening to voices …

Bridging the rodent to human translational gap: Marmosets as model systems for the study of Alzheimer's disease

SJ Sukoff Rizzo, G Homanics… - … Research & Clinical …, 2023 - Wiley Online Library
Introduction Our limited understanding of the mechanisms that trigger the emergence of
Alzheimer's disease (AD) has contributed to the lack of interventions that stop, prevent, or …

The devastating effects of sleep deprivation on memory: lessons from rodent models

P Chen, W Ban, W Wang, Y You, Z Yang - Clocks & Sleep, 2023 - mdpi.com
In this narrative review article, we discuss the role of sleep deprivation (SD) in memory
processing in rodent models. Numerous studies have examined the effects of SD on …