Raman spectral cytopathology for cancer diagnostic applications

D Traynor, I Behl, D O'dea, F Bonnier, S Nicholson… - Nature …, 2021 - nature.com
Raman spectroscopy can provide a rapid, label-free, nondestructive measurement of the
chemical fingerprint of a sample and has shown potential for cancer screening and …

Biomedical applications of vibrational spectroscopy: Oral cancer diagnostics

HJ Byrne, I Behl, G Calado, O Ibrahim, M Toner… - … Acta Part A: Molecular …, 2021 - Elsevier
Vibrational spectroscopy, based on either infrared absorption or Raman scattering, has
attracted increasing attention for biomedical applications. Proof of concept explorations for …

Deep learning methods for oral cancer detection using Raman spectroscopy

X Chang, M Yu, R Liu, R **g, J Ding, J **a, Z Zhu… - Vibrational …, 2023 - Elsevier
The Raman spectroscopy analysis has been applied to the detection and research of oral
cancer. One of the essential works in this technique is the Raman spectral data analysis …

Deep multi-feature fusion residual network for oral squamous cell carcinoma classification and its intelligent system using Raman spectroscopy

M Yu, J Ding, W Liu, X Tang, J **a, S Liang… - … Signal Processing and …, 2023 - Elsevier
Using fiber optic Raman spectroscopy and deep neural networks, we develop an intelligent
system which will be used to assist surgeons accurately and efficiently to identify oral …

YY1 accelerates oral squamous cell carcinoma progression through long non-coding RNA Kcnq1ot1/microRNA-506-3p/SYPL1 axis

Y Ding, H Duan, J Lin, X Zhang - Journal of Ovarian Research, 2022 - Springer
Abstract Objective Ying Yang1 (YY1) has already been discussed in oral squamous cell
carcinoma (OSCC), but the knowledge about its mediation on long non-coding RNA KCNQ1 …

Classification of cytological samples from oral potentially malignant lesions through Raman spectroscopy: A pilot study

I Behl, G Calado, A Vishwakarma, D Traynor… - … Acta Part A: Molecular …, 2022 - Elsevier
The potential of Raman microspectroscopy of exfoliated cells has been demonstrated for
oral cancer diagnosis. In this study, brush biopsies were collected from the buccal …

Identification of high-risk oral leukoplakia (OLK) using combined Raman spectroscopic analysis of brush biopsy and saliva samples: A proof of concept study

I Behl, G Calado, A Vishwakarma, D Traynor… - … Acta Part A: Molecular …, 2025 - Elsevier
The gold standard method of diagnosis of oral leukoplakia (OLK) is a tissue biopsy followed
by histological examination. Raman spectroscopic studies of cytological brush biopsy and …

Advances in Raman spectroscopy for characterising oral cancer and oral potentially malignant disorders

K Hanna, AL Asiedu, T Theurer, D Muirhead… - Expert Reviews in …, 2024 - cambridge.org
Oral cancer survival rates have seen little improvement over the past few decades. This is
mainly due to late detection and a lack of reliable markers to predict disease progression in …

Comparison between two cell collecting methods for liquid-based brush biopsies: a consecutive and retrospective study

K Gaida, L Deuerling, H Neumann, TW Remmerbach - BMC Oral Health, 2021 - Springer
Background This study compares two different cell collectors, the Orcellex Brush (rigid
brush) and the Cytobrush GT (nylon brush), using liquid-based cytology. A comparison of …

Identification of precancer oral lesions using minimally invasive sampling techniques and Raman microspectroscopy

I Behl, G Calado, S Flint, S Galvin… - Optical Biopsy XXI …, 2023 - spiedigitallibrary.org
The gold standard diagnosis of oral pre-cancer/cancer is an invasive biopsy followed by a
histological examination, which may present psychological trauma and risk of infection to …