Genomics of microbial plasmids: classification and identification based on replication and transfer systems and host taxonomy

M Shintani, ZK Sanchez, K Kimbara - Frontiers in microbiology, 2015 - frontiersin.org
Plasmids are important “vehicles” for the communication of genetic information between
bacteria. The exchange of plasmids transmits pathogenically and environmentally relevant …

Mobility of plasmids

C Smillie, MP Garcillán-Barcia… - Microbiology and …, 2010 - Am Soc Microbiol
Plasmids are key vectors of horizontal gene transfer and essential genetic engineering tools.
They code for genes involved in many aspects of microbial biology, including detoxication …

A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes

DH Haft, J Selengut, EF Mongodin… - PLoS computational …, 2005 - journals.plos.org
Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA
direct repeats found in many prokaryotic genomes. Repeats of 21–37 bp typically show …

Biological diversity of prokaryotic type IV secretion systems

CE Alvarez-Martinez, PJ Christie - Microbiology and Molecular …, 2009 - Am Soc Microbiol
Type IV secretion systems (T4SS) translocate DNA and protein substrates across prokaryotic
cell envelopes generally by a mechanism requiring direct contact with a target cell. Three …

CRISPR—a widespread system that provides acquired resistance against phages in bacteria and archaea

R Sorek, V Kunin, P Hugenholtz - Nature Reviews Microbiology, 2008 - nature.com
Arrays of clustered, regularly interspaced short palindromic repeats (CRISPRs) are
widespread in the genomes of many bacteria and almost all archaea. These arrays are …

The diversity of conjugative relaxases and its application in plasmid classification

MP Garcillán-Barcia, MV Francia… - FEMS microbiology …, 2009 - academic.oup.com
Bacterial conjugation is an efficient and sophisticated mechanism of DNA transfer among
bacteria. While mobilizable plasmids only encode a minimal MOB machinery that allows …

Archaeal DNA-import apparatus is homologous to bacterial conjugation machinery

LC Beltran, V Cvirkaite-Krupovic, J Miller… - Nature …, 2023 - nature.com
Conjugation is a major mechanism of horizontal gene transfer promoting the spread of
antibiotic resistance among human pathogens. It involves establishing a junction between a …

Evolutionary conservation of sequence and secondary structures in CRISPR repeats

V Kunin, R Sorek, P Hugenholtz - Genome biology, 2007 - Springer
Background Clustered regularly interspaced short palindromic repeats (CRISPRs) are a
novel class of direct repeats, separated by unique spacer sequences of similar length, that …

Extremely thermophilic microorganisms as metabolic engineering platforms for production of fuels and industrial chemicals

BM Zeldes, MW Keller, AJ Loder, CT Straub… - Frontiers in …, 2015 - frontiersin.org
Enzymes from extremely thermophilic microorganisms have been of technological interest
for some time because of their ability to catalyze reactions of industrial significance at …

Model organisms for genetics in the domain Archaea: methanogens, halophiles, Thermococcales and Sulfolobales

JA Leigh, SV Albers, H Atomi… - FEMS microbiology …, 2011 - academic.oup.com
The tree of life is split into three main branches: eukaryotes, bacteria, and archaea. Our
knowledge of eukaryotic and bacteria cell biology has been built on a foundation of studies …