Humans encounter mycobacterial species due to their ubiquity in different environmental
niches. In many individuals, pathogenic mycobacterial species may breach our first-line …

Whole genome metagenomic sequencing is a powerful platform enabling the simultaneous
identification of all genes from entirely different kingdoms of organisms in a complex sample …

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) and the
more recently discovered Mycobacterium lepromatosis (M. lepromatosis). The two leprosy …

Galleria mellonella (greater wax moth) larvae are used widely as surrogate infectious
disease models, due to ease of use and the presence of an innate immune system …

Leprosy is caused by Mycobacterium leprae (M. leprae) and M. lepromatosis, an obligate
intracellular organism, and over 200,000 new cases occur every year. M. leprae parasitizes …

Host–microbe interactions have been linked to health and disease states through the use of
microbial taxonomic profiling, mostly via 16S ribosomal RNA gene sequencing. However …

Mycobacterium lepromatosis was identified as a new species and second causal agent of
Hansen's disease (HD, or leprosy) in 2008, 150years after the disease was first attributed to …

Microbes are found on us, within us and around us. They inhabit virtually every environment
on the planet and the bacteria carried by an average human, mostly in their gut, outnumber …

Studying ancient DNA allows us to retrace the evolutionary history of human pathogens,
such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the …

Leprosy is a chronic human disease caused by the yet-uncultured pathogen Mycobacterium
leprae. Although readily curable with multidrug therapy (MDT), over 200,000 new cases are …