The role of antibiotics and heavy metals on the development, promotion, and dissemination of antimicrobial resistance in drinking water biofilms

V Rilstone, L Vignale, J Craddock, A Cushing, Y Filion… - Chemosphere, 2021 - Elsevier
Antimicrobial resistance (AMR), as well as the development of biofilms in drinking water
distribution systems (DWDSs), have become an increasing concern for public health and …

[HTML][HTML] Multidrug-resistant biofilms (MDR): Main mechanisms of tolerance and resistance in the food supply chain

FAE de Brito, APP de Freitas, MS Nascimento - Pathogens, 2022 - mdpi.com
Biofilms are mono-or multispecies microbial communities enclosed in an extracellular matrix
(EPS). They have high potential for dissemination and are difficult to remove. In addition …

Effect and mechanism of quorum sensing on horizontal transfer of multidrug plasmid RP4 in BAC biofilm

L Zhu, T Chen, L Xu, Z Zhou, W Feng, Y Liu… - Science of the Total …, 2020 - Elsevier
The widespread emergence of antibiotic resistance genes (ARGs) in drinking water systems
endangers human health, and may be exacerbated by their horizontal gene transfer (HGT) …

[HTML][HTML] Combatting biofilm-mediated infections in clinical settings by targeting quorum sensing

A Mitra - The Cell Surface, 2024 - Elsevier
Biofilm-associated infections constitute a significant challenge in managing infectious
diseases due to their high resistance to antibiotics and host immune responses. Biofilms are …

Crumbling the castle: targeting DNABII proteins for collapsing bacterial biofilms as a therapeutic approach to treat disease and combat antimicrobial resistance

JV Rogers, VL Hall, CC McOsker - Antibiotics, 2022 - mdpi.com
Antimicrobial resistance (AMR) is a concerning global threat that, if not addressed, could
lead to increases in morbidity and mortality, coupled with societal and financial burdens. The …

[HTML][HTML] Modelling drinking water biofilms: bacterial adhesion and Legionella pneumophila necrotrophic growth

J Vincent, A Tenore, MR Mattei, L Frunzo - Communications in Nonlinear …, 2024 - Elsevier
We propose a mathematical model to simulate the establishment and growth of a drinking
water distribution system biofilm, focusing on the influence of ionic strength on bacterial …

The emerging challenge of Enterococcus faecalis endocarditis after transcatheter aortic valve implantation: time for innovative treatment approaches

JA Cusumano, AP Kalogeropoulos… - Clinical Microbiology …, 2024 - journals.asm.org
Infective endocarditis (IE) is a life-threatening infection that has nearly doubled in
prevalence over the last two decades due to the increase in implantable cardiac devices …

Modelling plasmid-mediated horizontal gene transfer in biofilms

J Vincent, A Tenore, MR Mattei, L Frunzo - Bulletin of mathematical biology, 2024 - Springer
In this study, we present a mathematical model for plasmid spread in a growing biofilm,
formulated as a nonlocal system of partial differential equations in a 1-D free boundary …

Development of an integrated ultrasonic biofilm detachment model for biofilm thickness control in membrane aerated bioreactors

M Ghasemi, S Chang, S Sivaloganathan - Applied Mathematical Modelling, 2021 - Elsevier
Controlling biofilm thickness in an aerated membrane biofilm reactor (MBfR) has been
recognized as a key for MBfRs to achieve a long-term stable performance. In this context …

Regulatory Effect of Irresistin-16 on Competitive Dual-Species Biofilms Composed of Streptococcus mutans and Streptococcus sanguinis

X Hu, M Wang, Y Shen, L Zhang, Y Pan, Y Sun… - Pathogens, 2022 - mdpi.com
Based on the ecological plaque hypothesis, suppressing opportunistic pathogens within
biofilms, rather than killing microbes indiscriminately, could be a biofilm control strategy for …