Photoactivatable protherapeutic nanomedicine for cancer

Y Zhang, C Xu, X Yang, K Pu - Advanced Materials, 2020 - Wiley Online Library
Therapeutic systems with site‐specific pharmaceutical activation hold great promise to
enhance therapeutic efficacy while reducing systemic toxicity in cancer therapy. With …

Photoresponsive biomaterials for targeted drug delivery and 4D cell culture

ER Ruskowitz, CA DeForest - Nature Reviews Materials, 2018 - nature.com
Biological signalling is regulated through a complex and tightly choreographed interplay
between cells and their extracellular matrix. The spatiotemporal control of these interactions …

Rational design of cancer nanomedicine for simultaneous stealth surface and enhanced cellular uptake

Q **, Y Deng, X Chen, J Ji - Acs Nano, 2019 - ACS Publications
Owing to the complex and still not fully understood physiological environment, the
development of traditional nanosized drug delivery systems is very challenging for precision …

Plasmonic optical tweezers for particle manipulation: principles, methods, and applications

Y Ren, Q Chen, M He, X Zhang, H Qi, Y Yan - ACS nano, 2021 - ACS Publications
Inspired by the idea of combining conventional optical tweezers with plasmonic
nanostructures, a technique named plasmonic optical tweezers (POT) has been widely …

Hierarchical targeting strategy for enhanced tumor tissue accumulation/retention and cellular internalization

S Wang, P Huang, X Chen - Advanced Materials, 2016 - Wiley Online Library
Targeted delivery of therapeutic agents is an important way to improve the therapeutic index
and reduce side effects. To design nanoparticles for targeted delivery, both enhanced tumor …

Photoresponsive nanoparticles for drug delivery

AY Rwei, W Wang, DS Kohane - Nano today, 2015 - Elsevier
Externally triggerable drug delivery systems provide a strategy for the delivery of therapeutic
agents preferentially to a target site, presenting the ability to enhance therapeutic efficacy …

Hypoxia-responsive polymeric nanoparticles for tumor-targeted drug delivery

T Thambi, VG Deepagan, HY Yoon, HS Han, SH Kim… - Biomaterials, 2014 - Elsevier
Hypoxia is a condition found in various intractable diseases. Here, we report self-assembled
nanoparticles which can selectively release the hydrophobic agents under hypoxic …

Resonance energy transfer-promoted photothermal and photodynamic performance of gold–copper sulfide yolk–shell nanoparticles for chemophototherapy of cancer

Y Chang, Y Cheng, Y Feng, H Jian, L Wang, X Ma… - Nano …, 2018 - ACS Publications
Gold (Au) core@ void@ copper sulfide (CuS) shell (Au–CuS) yolk–shell nanoparticles
(YSNPs) were prepared in the present study for potential chemo-, photothermal, and …

[HTML][HTML] Cell-penetrating peptide-based delivery of macromolecular drugs: development, strategies, and progress

Z Sun, J Huang, Z Fishelson, C Wang, S Zhang - Biomedicines, 2023 - mdpi.com
Cell-penetrating peptides (CPPs), developed for more than 30 years, are still being
extensively studied due to their excellent delivery performance. Compared with other …

Challenge to overcome current limitations of cell-penetrating peptides

GC Kim, DH Cheon, Y Lee - Biochimica et Biophysica Acta (BBA)-Proteins …, 2021 - Elsevier
The penetration of biological membranes is a prime obstacle for the delivery of
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …