This paper reviews the research evidence concerning the intergenerational transmission of
trauma effects and the possible role of epigenetic mechanisms in this transmission. Two …

This year is the tenth anniversary of the publication in this journal of a model suggesting the
existence of'tumour progenitor genes'. These genes are epigenetically disrupted at the …

The process of aging results in a host of changes at the cellular and molecular levels, which
include senescence, telomere shortening, and changes in gene expression. Epigenetic …

With regards to health, chromium (Cr) is an ambiguous chemical element. Although it is
considered to be an important micronutrient, it also is connected with several pathologies …

DNA methylation (DNAm) is important in brain development and is potentially important in
schizophrenia. We characterized DNAm in prefrontal cortex from 335 non-psychiatric …

Genome-wide association studies (GWASs) have enabled the discovery of common genetic
variation contributing to normal and pathological traits and clinical drug responses, but …

Complex and dynamic networks of molecules are involved in human diseases. High-
throughput technologies enable omics studies interrogating thousands to millions of makers …

Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

Endocrine disrupting chemicals (EDCs), including the mass-produced component of
plastics, bisphenol A (BPA) are widely prevalent in aquatic and terrestrial habitats. Many …

Epigenetic modifications in response to traumatic experience and stress are emerging as
important factors in the long-term biological trajectories leading to stress-related psychiatric …