An update on current therapeutic drugs treating COVID-19
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented …
[HTML][HTML] Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen
Ivermectin proposes many potentials effects to treat a range of diseases, with its
antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective …
antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective …
[HTML][HTML] Effect of ivermectin on time to resolution of symptoms among adults with mild COVID-19: a randomized clinical trial
Importance Ivermectin is widely prescribed as a potential treatment for COVID-19 despite
uncertainty about its clinical benefit. Objective To determine whether ivermectin is an …
uncertainty about its clinical benefit. Objective To determine whether ivermectin is an …
[HTML][HTML] The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
Although several clinical trials are now underway to test possible therapies, the worldwide
response to the COVID-19 outbreak has been largely limited to monitoring/containment. We …
response to the COVID-19 outbreak has been largely limited to monitoring/containment. We …
The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer
SNY Yang, SC Atkinson, C Wang, A Lee… - Antiviral research, 2020 - Elsevier
Infection by RNA viruses such as human immunodeficiency virus (HIV)-1, influenza, and
dengue virus (DENV) represent a major burden for human health worldwide. Although RNA …
dengue virus (DENV) represent a major burden for human health worldwide. Although RNA …
The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind, placebo …
Background Ivermectin inhibits the replication of SARS-CoV-2 in vitro at concentrations not
readily achievable with currently approved doses. There is limited evidence to support its …
readily achievable with currently approved doses. There is limited evidence to support its …
[HTML][HTML] Review of the emerging evidence demonstrating the efficacy of ivermectin in the prophylaxis and treatment of COVID-19
Background: After COVID-19 emerged on US shores, providers began reviewing the
emerging basic science, translational, and clinical data to identify potentially effective …
emerging basic science, translational, and clinical data to identify potentially effective …
[HTML][HTML] Ivermectin and COVID-19: kee** rigor in times of urgency
Ivermectin is a widely used drug for the treatment and control of several neglected tropical
diseases. 1 The drug has an excellent safety profile, with more than 2.5 billion doses …
diseases. 1 The drug has an excellent safety profile, with more than 2.5 billion doses …
Avermectin derivatives, pharmacokinetics, therapeutic and toxic dosages, mechanism of action, and their biological effects
Avermectins are a group of drugs that occurs naturally as a product of fermenting
Streptomyces avermitilis, an actinomycetes, isolated from the soil. Eight different structures …
Streptomyces avermitilis, an actinomycetes, isolated from the soil. Eight different structures …
Ivermectin: an anthelmintic, an insecticide, and much more
Here we tell the story of ivermectin, describing its anthelmintic and insecticidal actions and
recent studies that have sought to reposition ivermectin for the treatment of other diseases …
recent studies that have sought to reposition ivermectin for the treatment of other diseases …