Oxidative stress is increasingly recognized as a central event contributing to the
degeneration of dopaminergic neurons in the pathogenesis of Parkinson's disease (PD) …

In this review article, emphasis is placed on the critical survey of available data concerning
modified nucleobase and 2-deoxyribose products that have been identified in cellular DNA …

Parkinson disease (PD), the most common neurodegenerative movement disorder, is
associated with selective degeneration of nigrostriatal dopamine neurons. Although the …

Background: Cells respond to environmental stressors through several key pathways,
including response to reactive oxygen species (ROS), nutrient and ATP sensing, DNA …

The burden of heart failure (HF) in terms of health care expenditures, hospitalizations, and
mortality is substantial and growing. The failing heart has been described as “energy …

DNA damage is any modification to the structure of DNA that alters its coding properties
and/or interferes with cell processes. One major consequence of oxidative stress is DNA …

DNA damage can cause (and result from) oxidative stress and mitochondrial impairment,
both of which are implicated in the pathogenesis of Parkinson's disease (PD). We therefore …

Accumulating evidence from numerous comprehensive studies has demonstrated that blue
light, in particular high‐energy visible light, can exert a range of harmful effects on skin cells …

This survey focuses on the critical evaluation of the main methods that are currently
available for monitoring single and complex oxidatively generated damage to cellular DNA …

RECQL4 is associated with Rothmund–Thomson Syndrome (RTS), a rare autosomal
recessive disorder characterized by premature aging, genomic instability, and cancer …