Living biological systems, ranging from single cells to whole organisms, can sense, process
information, and actuate in response to changing environmental conditions. Inspired by …

Plants being sessile are constantly challenged by numerous abiotic stressors that
jeopardize their survival. Drought stress is a major constraint in sustainable agriculture that …

Communities of microbes play important roles in natural environments and hold great
potential for deploying division-of-labor strategies in synthetic biology and bioproduction …

Microbial coculture engineering has emerged as a promising strategy for biomanufacturing.
Stability and self-regulation pose a significant challenge for the generation of intrinsically …

Targeted therapy and immunotherapy have brought hopes for precision cancer treatment.
However, complex physiological barriers and tumor immunosuppression result in poor …

Powerful distributed computing can be achieved by communicating cells that individually
perform simple operations. Here, we report design software to divide a large genetic circuit …

Presently, agriculture worldwide is facing the major challenge of feeding the increasing
population sustainably. The conventional practices have not only failed to meet the …

Synthetic microbial community (SynCom) biosensors are a promising technology for
detecting and responding to environmental cues and target molecules. SynCom biosensors …

In nature, quorum sensing is one of the mechanisms bacterial populations use to
communicate with their own species or across species to coordinate behaviours. For the last …

Complex biological systems in nature comprise cells that act collectively to solve
sophisticated tasks. Synthetic biological systems, in contrast, are designed for specific tasks …