Progress in 3D bioprinting technology for tissue/organ regenerative engineering

I Matai, G Kaur, A Seyedsalehi, A McClinton… - Biomaterials, 2020‏ - Elsevier
Escalating cases of organ shortage and donor scarcity worldwide are alarming reminders of
the need for alternatives to allograft tissues. Within the last three decades, research efforts in …

[HTML][HTML] Mechanics in the nervous system: from development to disease

EK Pillai, K Franze - Neuron, 2024‏ - cell.com
Physical forces are ubiquitous in biological processes across scales and diverse contexts.
This review highlights the significance of mechanical forces in nervous system development …

Microfluidic bioprinting of tough hydrogel-based vascular conduits for functional blood vessels

D Wang, S Maharjan, X Kuang, Z Wang, LS Mille… - Science …, 2022‏ - science.org
Three-dimensional (3D) bioprinting of vascular tissues that are mechanically and
functionally comparable to their native counterparts is an unmet challenge. Here, we …

Deep learning-based predictive identification of neural stem cell differentiation

Y Zhu, R Huang, Z Wu, S Song, L Cheng… - Nature communications, 2021‏ - nature.com
The differentiation of neural stem cells (NSCs) into neurons is proposed to be critical in
devising potential cell-based therapeutic strategies for central nervous system (CNS) …

[HTML][HTML] A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury

Z Li, T Zhao, J Ding, H Gu, Q Wang, Y Wang, D Zhang… - Bioactive materials, 2023‏ - Elsevier
Spinal cord injury (SCI) is an overwhelming and incurable disabling event accompanied by
complicated inflammation-related pathological processes, such as excessive reactive …

ROS‐scavenging hydrogels synergize with neural stem cells to enhance spinal cord injury repair via regulating microenvironment and facilitating nerve regeneration

D Liu, G Lu, B Shi, H Ni, J Wang, Y Qiu… - Advanced …, 2023‏ - Wiley Online Library
Although stem cell‐based therapy is recognized as a promising therapeutic strategy for
spinal cord injury (SCI), its efficacy is greatly limited by local reactive oxygen species (ROS) …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G **… - Chemical …, 2017‏ - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Tunable hydrogel viscoelasticity modulates human neural maturation

JG Roth, MS Huang, RS Navarro, JT Akram… - Science …, 2023‏ - science.org
Human-induced pluripotent stem cells (hiPSCs) have emerged as a promising in vitro model
system for studying neurodevelopment. However, current models remain limited in their …

[HTML][HTML] Printability–A key issue in extrusion-based bioprinting

S Naghieh, X Chen - Journal of pharmaceutical analysis, 2021‏ - Elsevier
Abstract Three-dimensional (3D) extrusion-based bioprinting is widely used in tissue
engineering and regenerative medicine to create cell-incorporated constructs or scaffolds …

[HTML][HTML] An injectable, self-healing, electroconductive extracellular matrix-based hydrogel for enhancing tissue repair after traumatic spinal cord injury

Y Luo, L Fan, C Liu, H Wen, S Wang, P Guan, D Chen… - Bioactive materials, 2022‏ - Elsevier
Injectable biomaterial-based treatment is a promising strategy to enhance tissue repair after
traumatic spinal cord injury (SCI) by bridging cavity spaces. However, there are limited …