ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

PM Thompson, N Jahanshad, CRK Ching… - Translational …, 2020‏ - nature.com
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …

Harmonizing the neurobiology and treatment of obsessive-compulsive disorder

WK Goodman, EA Storch… - American Journal of …, 2021‏ - psychiatryonline.org
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling
disorder. The only established first-line treatments for OCD are exposure and response …

Functional connectivity signatures of major depressive disorder: machine learning analysis of two multicenter neuroimaging studies

S Gallo, A El-Gazzar, P Zhutovsky, RM Thomas… - Molecular …, 2023‏ - nature.com
The promise of machine learning has fueled the hope for develo** diagnostic tools for
psychiatry. Initial studies showed high accuracy for the identification of major depressive …

Obsessive‐compulsive disorder: Etiology, neuropathology, and cognitive dysfunction

B Jalal, SR Chamberlain, BJ Sahakian - Brain and behavior, 2023‏ - Wiley Online Library
Background This review provides an overview of obsessive‐compulsive disorder (OCD)
symptoms, including the four partially distinct subtypes of the disorder, current diagnostic …

Recent advances in psychoradiology

L Luo, W You, MP DelBello, Q Gong… - Physics in Medicine & …, 2022‏ - iopscience.iop.org
Psychiatry, as a field, lacks objective markers for diagnosis, progression, treatment planning,
and prognosis, in part due to difficulties studying the brain in vivo, and diagnoses are based …

The functional connectome in obsessive-compulsive disorder: resting-state mega-analysis and machine learning classification for the ENIGMA-OCD consortium

WB Bruin, Y Abe, P Alonso, A Anticevic… - Molecular …, 2023‏ - nature.com
Current knowledge about functional connectivity in obsessive-compulsive disorder (OCD) is
based on small-scale studies, limiting the generalizability of results. Moreover, the majority …

An overview of the first 5 years of the ENIGMA obsessive–compulsive disorder working group: The power of worldwide collaboration

OA Van den Heuvel, PSW Boedhoe… - Human brain …, 2022‏ - Wiley Online Library
Neuroimaging has played an important part in advancing our understanding of the
neurobiology of obsessive–compulsive disorder (OCD). At the same time, neuroimaging …

Sampling inequalities affect generalization of neuroimaging-based diagnostic classifiers in psychiatry

Z Chen, B Hu, X Liu, B Becker, SB Eickhoff, K Miao… - BMC medicine, 2023‏ - Springer
Background The development of machine learning models for aiding in the diagnosis of
mental disorder is recognized as a significant breakthrough in the field of psychiatry …

Evaluation of risk of bias in neuroimaging-based artificial intelligence models for psychiatric diagnosis: a systematic review

Z Chen, X Liu, Q Yang, YJ Wang, K Miao… - JAMA Network …, 2023‏ - jamanetwork.com
Importance Neuroimaging-based artificial intelligence (AI) diagnostic models have
proliferated in psychiatry. However, their clinical applicability and reporting quality (ie …

Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci

NI Strom, ZF Gerring, M Galimberti, D Yu… - medRxiv, 2024‏ - pmc.ncbi.nlm.nih.gov
Obsessive-compulsive disorder (OCD) affects~ 1% of the population and exhibits a high
SNP-heritability, yet previous genome-wide association studies (GWAS) have provided …