New insights into mechanisms behind miscarriage

EC Larsen, OB Christiansen, AM Kolte, N Macklon - BMC medicine, 2013 - Springer
Sporadic miscarriage is the most common complication of early pregnancy. Two or three
consecutive pregnancy losses is a less common phenomenon, and this is considered a …

Recurrent miscarriage

DW Branch, C Heuser - … and Infertility: Integrating Modern Clinical and …, 2010 - Springer
Recurrent miscarriage is a common pathology fond in 1% to 5% of reproductively active
couples. This chapter discusses the possible causes of recurrent miscarriage, and …

Cell–cell contact with proinflammatory macrophages enhances the immunotherapeutic effect of mesenchymal stem cells in two abortion models

Y Li, D Zhang, L Xu, L Dong, J Zheng, Y Lin… - Cellular & molecular …, 2019 - nature.com
Mesenchymal stem cells (MSCs), which are pluripotent cells with immunomodulatory
properties, have been considered good candidates for the therapy of several immune …

Natural selection of human embryos: impaired decidualization of endometrium disables embryo-maternal interactions and causes recurrent pregnancy loss

M Salker, G Teklenburg, M Molokhia, S Lavery, G Trew… - PloS one, 2010 - journals.plos.org
Background Recurrent pregnancy loss (RPL), defined as 3 or more consecutive
miscarriages, is widely attributed either to repeated chromosomal instability in the conceptus …

Depression and emotional stress is highly prevalent among women with recurrent pregnancy loss

AM Kolte, LR Olsen, EM Mikkelsen… - Human …, 2015 - academic.oup.com
STUDY QUESTION Is the prevalence of psychological stress and moderate/severe
depression higher for women with recurrent pregnancy loss (RPL) than pregnancy planners …

Genetics of recurrent miscarriage: challenges, current knowledge, future directions

K Rull, L Nagirnaja, M Laan - Frontiers in genetics, 2012 - frontiersin.org
Recurrent miscarriage (RM) occurs in 1–3% of couples aiming at childbirth. Due to
multifactorial etiology the clinical diagnosis of RM varies. The design of genetic/“omics” …

Recurrent miscarriage: current concepts in diagnosis and treatment

B Toth, U Jeschke, N Rogenhofer, C Scholz… - Journal of reproductive …, 2010 - Elsevier
Although recurrent miscarriage (RM) affects only 1–3% of couples, it has a major influence
on the wellbeing and psychosocial status of patients. Therefore, research into improved …

The molecular basis of recurrent pregnancy loss: impaired natural embryo selection

G Teklenburg, M Salker, C Heijnen… - Molecular human …, 2010 - academic.oup.com
Recurrent pregnancy loss (RPL) is a common and distressing disorder. Chromosomal errors
in the embryo are the single most common cause, whereas uterine factors are invariably …

Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010–11 and 2011–12

JG Donahue, BA Kieke, JP King, F DeStefano… - Vaccine, 2017 - Elsevier
Introduction Inactivated influenza vaccine is recommended in any stage of pregnancy, but
evidence of safety in early pregnancy is limited, including for vaccines containing …

Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss

Y Li, J Zhang, DI Zhang, X Hong, Y Tao, S Wang… - Science …, 2017 - science.org
Pregnancy loss occurs in about 15% of clinically recognized pregnancies, and defective
maternal-fetal immune tolerance contributes to more than 50% of these events. We found …