As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a crucial role in
cancer development. Since the discovery of the identity and clinical functions of miRNAs …

Abstract MicroRNA-34 (miR-34) has been reported to be dysregulated in various human
cancers and regarded as a tumor suppressive microRNA because of its synergistic effect …

Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for
prevention and therapy of colorectal cancer/CRC. However, the exact mechanism of action …

Simple Summary The dysregulation of the miR-34 family has been shown to play an
important role in tumorigenesis and cancer progression. In this review, we summarized the …

Inflammatory breast cancer (IBC) is a rare and aggressive disease that accounts for~ 2–4%
of all breast cancers. However, despite its low incidence rate, IBC is responsible for 7–10 …

MicroRNAs (miRNAs) are pervasively expressed and regulate most biological functions.
They function by modulating transcriptional and translational programs and therefore they …

MicroRNA miR-34a is recognized as a master regulator of tumor suppression. The strategy
of miR-34a replacement has been investigated in clinical trials as the first attempt of miRNA …

The incidence of heart failure is primarily flat or declining for a presumably reflecting better
management of cardiovascular diseases, but that of heart failure with preserved ejection …

Genotoxic colibactin-producing pks+ Escherichia coli induce DNA double-strand breaks,
mutations, and promote tumor development in mouse models of colorectal cancer (CRC) …

Extracellular vesicles (EVs) are known to play important roles in cell-cell communication.
Here we investigated the role of muscle-derived EVs and their microRNAs in the loss of …