Neuropeptides released by hypothalamic neurons play a major role in the regulation of
feeding, acting both within the hypothalamus, and at other appetite regulating centres …

This review aims to give a brief overview of NPY receptor distribution and physiology in the
brain and summarizes series of studies, test by test and region by region, aimed at …

INTRODUCTION Brain function is often compared to an orchestral ensemble, where
subgroups of neurons that have similar activity are analogous to different types of …

The development of clinically useful drugs to modify brain neuropeptide activities is yielding
new therapeutic possibilities. Although psychiatric payoffs from the study of these systems …

Metabolic syndrome (MetS) is a cluster ofassociated metabolic traits that collectively confer
unsurpassed risk for development of cardiovascular disease (CVD) and type 2 diabetes …

The peptidic neurotransmitter neuropeptide Y (NPY) has received great attention because it
has been implicated in the regulation of several organ systems. In particular, NPY is …

Neuropeptide Y (NPY) is a highly conserved neuropeptide with orexigenic actions in
discrete hypothalamic nuclei that plays a role in regulating energy homeostasis. NPY …

Abstract Neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP) belong
to the NPY hormone family and activate a class of receptors called the Y‐receptors, and also …

The three peptides pancreatic polypeptide (PP), peptide YY (PYY), and neuropeptide Y
(NPY) share a similar structure known as the PP-fold. There are four known human G …

The balance between energy intake and energy expenditure establishes and preserves a
'set-point'body weight. The latter is comprised of three major components including …