Hacking the brain: dimensions of cognitive enhancement

M Dresler, A Sandberg, C Bublitz, K Ohla… - ACS chemical …, 2018 - ACS Publications
In an increasingly complex information society, demands for cognitive functioning are
growing steadily. In recent years, numerous strategies to augment brain function have been …

Attitudes toward pharmacological cognitive enhancement—a review

KJ Schelle, N Faulmüller, L Caviola… - Frontiers in systems …, 2014 - frontiersin.org
A primary means for the augmentation of cognitive brain functions is “pharmacological
cognitive enhancement”(PCE). The term usually refers to the off-label use of medical …

Catecholaminergic challenge uncovers distinct Pavlovian and instrumental mechanisms of motivated (in) action

JC Swart, MI Froböse, JL Cook, DEM Geurts, MJ Frank… - Elife, 2017 - elifesciences.org
Catecholamines modulate the impact of motivational cues on action. Such motivational
biases have been proposed to reflect cue-based,'Pavlovian'effects. Here, we assess …

[HTML][HTML] Smart drugs and neuroenhancement: what do we know?

M Esposito, G Cocimano, F Ministrieri… - Frontiers in Bioscience …, 2021 - imrpress.com
Introduction: Smart drugs are among the most common drugs used by students. It is
estimated that they are second in incidence after cannabis. Although they are usually used …

Dose-response effects of d-amphetamine on effort-based decision-making and reinforcement learning

HE Soder, JA Cooper, P Lopez-Gamundi… - …, 2021 - nature.com
Effort-related decision-making and reward learning are both dopamine-dependent, but
preclinical research suggests they depend on different dopamine signaling dynamics …

How effective are pharmaceuticals for cognitive enhancement in healthy adults? A series of meta-analyses of cognitive performance during acute administration of …

CA Roberts, A Jones, H Sumnall, SH Gage… - European …, 2020 - Elsevier
Modafinil, methyphenidate (MPH) and d-amphetamine (d-amph) are putative cognitive
enhancers. However, efficacy of cognitive enhancement has yet to be fully established. We …

Effects of dopamine on reinforcement learning and consolidation in Parkinson's disease

JP Grogan, D Tsivos, L Smith, BE Knight, R Bogacz… - Elife, 2017 - elifesciences.org
Emerging evidence suggests that dopamine may modulate learning and memory with
important implications for understanding the neurobiology of memory and future therapeutic …

Using pharmacological manipulations to study the role of dopamine in human reward functioning: A review of studies in healthy adults

HE Webber, P Lopez-Gamundi, SN Stamatovich… - Neuroscience & …, 2021 - Elsevier
Dopamine (DA) plays a key role in reward processing and is implicated in psychological
disorders such as depression, substance use, and schizophrenia. The role of DA in reward …

Predicting beneficial effects of atomoxetine and citalopram on response inhibition in P arkinson's disease with clinical and neuroimaging measures

Z Ye, CL Rae, C Nombela, T Ham… - Human brain …, 2016 - Wiley Online Library
Recent studies indicate that selective noradrenergic (atomoxetine) and serotonergic
(citalopram) reuptake inhibitors may improve response inhibition in selected patients with …

Classics in chemical neuroscience: methylphenidate

CJ Wenthur - ACS chemical neuroscience, 2016 - ACS Publications
As the first drug to see widespread use for the treatment of attention deficit hyperactivity
disorder (ADHD), methylphenidate was the forerunner and catalyst to the modern era of …