Thyroid hormones and cancer: a comprehensive review of preclinical and clinical studies

E Krashin, A Piekiełko-Witkowska, M Ellis… - Frontiers in …, 2019 - frontiersin.org
Thyroid hormones take major part in normal growth, development and metabolism. Over a
century of research has supported a relationship between thyroid hormones and the …

Thyroid hormones interaction with immune response, inflammation and non-thyroidal illness syndrome

R De Luca, PJ Davis, HY Lin, F Gionfra… - Frontiers in cell and …, 2021 - frontiersin.org
The interdependence between thyroid hormones (THs), namely, thyroxine and
triiodothyronine, and immune system is nowadays well-recognized, although not yet fully …

Recent advances in doxorubicin formulation to enhance pharmacokinetics and tumor targeting

J Lee, MK Choi, IS Song - Pharmaceuticals, 2023 - mdpi.com
Doxorubicin (DOX), a widely used drug in cancer chemotherapy, induces cell death via
multiple intracellular interactions, generating reactive oxygen species and DNA-adducted …

Molecular functions of thyroid hormone signaling in regulation of cancer progression and anti-apoptosis

YC Liu, CT Yeh, KH Lin - International Journal of Molecular Sciences, 2019 - mdpi.com
Several physiological processes, including cellular growth, embryonic development,
differentiation, metabolism and proliferation, are modulated by genomic and nongenomic …

Thyroid hormone action and liver disease, a complex interplay

L Marino, A Kim, B Ni, FS Celi - Hepatology, 2025 - journals.lww.com
Thyroid hormone action is involved in virtually all physiological processes. It is well known
that the liver and thyroid are intimately linked, with thyroid hormone playing important roles …

Tumor microenviroment and hepatocellular carcinoma metastasis

H Wang, L Chen - Journal of gastroenterology and hepatology, 2013 - Wiley Online Library
The cross talk between tumor cells and the surrounding peritumoral stroma has been
extensively studied as a dynamic system involving the processes of hepatocarcinogenesis …

Role of thyroid hormones in the neoplastic process: an overview

IM Goemann, M Romitti, ELS Meyer… - Endocrine-related …, 2017 - erc.bioscientifica.com
Thyroid hormones (TH) are critical regulators of several physiological processes, which
include development, differentiation and growth in virtually all tissues. In past decades …

The role of thyroid hormones in hepatocyte proliferation and liver cancer

F Gionfra, P De Vito, V Pallottini, HY Lin… - Frontiers in …, 2019 - frontiersin.org
Thyroid hormones T3 and T4 (thyroxine) control a wide variety of effects related to
development, differentiation, growth and metabolism, through their interaction with nuclear …

Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming

MA Kowalik, E Puliga, L Cabras, P Sulas, A Petrelli… - Journal of …, 2020 - Elsevier
Background & Aims Only limited therapeutic options are currently available for
hepatocellular carcinoma (HCC), making the development of effective alternatives essential …

O‐GlcNAcylated LARP1 positively regulated by circCLNS1A facilitates hepatoblastoma progression through DKK4/β‐catenin signalling

Z Cui, J He, J Zhu, W Ni, L Liu, Z Bian… - Clinical and …, 2023 - Wiley Online Library
Background Accumulating studies have shown that La‐related protein 1 (LARP1) is involved
in the occurrence and development of various tumours. However, the expression pattern …