Analysis of the conserved protective epitopes of hemagglutinin on influenza A viruses

C Jiao, B Wang, P Chen, Y Jiang, J Liu - Frontiers in Immunology, 2023 - frontiersin.org
The conserved protective epitopes of hemagglutinin (HA) are essential to the design of a
universal influenza vaccine and new targeted therapeutic agents. Over the last 15 years …

[HTML][HTML] Host innate antiviral response to influenza A virus infection: from viral sensing to antagonism and escape

W An, S Lakhina, J Leong, K Rawat, M Husain - Pathogens, 2024 - mdpi.com
Influenza virus possesses an RNA genome of single-stranded, negative-sensed, and
segmented configuration. Influenza virus causes an acute respiratory disease, commonly …

A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity

Y Li, G Liang, Z Chen, K Zhang, J Liang… - Acta Pharmacologica …, 2024 - nature.com
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human
health, causing pandemics with high mortality and pathogenicity. Given the emergence of …

Biomedical potency and mechanisms of marine polysaccharides and oligosaccharides: A review

Y Wang, X Guo, C Huang, C Shi, X **ang - International Journal of …, 2024 - Elsevier
Derived from bountiful marine organisms (predominantly algae, fauna, and
microorganisms), marine polysaccharides and marine oligosaccharides are intricate …

Monoclonal antibody applications in travel medicine

HK de Jong, MP Grobusch - Tropical Diseases, Travel Medicine and …, 2024 - Springer
For decades, immunoglobulin preparations have been used to prevent or treat infectious
diseases. Since only a few years, monoclonal antibody applications (mAbs) are taking flight …

Antiviral Medications for Treatment of Nonsevere Influenza: A Systematic Review and Network Meta-Analysis

Y Gao, Y Zhao, M Liu, S Luo, Y Chen… - JAMA Internal …, 2025 - jamanetwork.com
Importance The optimal antiviral drug for treatment of nonsevere influenza remains unclear.
Objective To compare effects of antiviral drugs for treating nonsevere influenza. Data …

LDC000067, a CDK9 inhibitor, unveils promising results in suppressing influenza virus infections in vitro and in vivo

M Zhang, X Lian, Y Gao, L Jiang, Z Li… - Antimicrobial Agents …, 2024 - journals.asm.org
Influenza virus infections continue to pose a significant threat to public health. Current anti-
influenza drugs target viral proteins; however, the emergence of resistant strains has …

Lactobacillus plantarum GUANKE modulate anti-viral function of dendritic cells in mice

S Lu, S He, K Yue, J Mi, Y Huang, L Song… - International …, 2024 - Elsevier
GUANKE is a Lactobacillus plantarum isolated from the feces of healthy volunteer. We have
previously shown that GUANKE enhances the efficacy of the SARS-CoV-2 vaccine and …

Molecular modelling studies of substituted indole derivatives as novel influenza a virus inhibitors

M Abdullahi, A Uzairu, GA Shallangwa… - Journal of …, 2025 - Taylor & Francis
The emergence of drug-resistant strains motivate researchers to find new innovative anti-IAV
candidates with a different mode of action. In this work, molecular modelling strategies, such …

[HTML][HTML] Oral probiotic extracellular vesicle therapy mitigates Influenza A Virus infection via blunting IL-17 signaling

H Zhou, W Huang, J Li, P Chen, L Shen, W Huang… - Bioactive Materials, 2025 - Elsevier
The influenza A virus (IAV) damages intestinal mucosal tissues beyond the respiratory tract.
Probiotics play a crucial role in maintaining the balance and stability of the intestinal …