Programming mammalian cell behaviors by physical cues
In recent decades, the field of synthetic biology has witnessed remarkable progress, driving
advances in both research and practical applications. One pivotal area of development …
advances in both research and practical applications. One pivotal area of development …
Application of super-resolution microscopy in mitochondria-dynamic diseases
W Zou, L Yang, H Lu, M Li, D Ji, J Slone… - Advanced Drug Delivery …, 2023 - Elsevier
Limited by spatial and temporal resolution, traditional optical microscopy cannot image the
delicate ultra-structure organelles and sub-organelles. The emergence of super-resolution …
delicate ultra-structure organelles and sub-organelles. The emergence of super-resolution …
Revealing Mitochondrion–Lysosome Dynamic Interactions and pH Variations in Live Cells with a pH-Sensitive Fluorescent Probe
J Wang, JT Yan, ST Zeng, W Shao, GX Tang… - Analytical …, 2023 - ACS Publications
Mitochondrion–lysosome interactions have garnered significant attention in recent research.
Numerous studies have shown that mitochondrion–lysosome interactions, including …
Numerous studies have shown that mitochondrion–lysosome interactions, including …
Repurposing cyanine photoinstability to develop near-infrared light-activatable nanogels for in vivo cargo delivery
The favorable properties of cyanines (eg, near-infrared (NIR) absorbance and emission)
have made this class of dyes popular for a wide variety of biomedical applications. However …
have made this class of dyes popular for a wide variety of biomedical applications. However …
2D MoS2 and BN Nanosheets Damage Mitochondria through Membrane Penetration
K Qiu, W Zou, Z Fang, Y Wang, S Bell, X Zhang… - ACS …, 2023 - ACS Publications
With the progression of nanotechnology, a growing number of nanomaterials have been
created and incorporated into organisms and ecosystems, which raises significant concern …
created and incorporated into organisms and ecosystems, which raises significant concern …
Constant conversion rate of endolysosomes revealed by a pH-sensitive fluorescent probe
Endolysosome dynamics plays an important role in autophagosome biogenesis. Hence,
imaging the subcellular dynamics of endolysosomes using high-resolution fluorescent …
imaging the subcellular dynamics of endolysosomes using high-resolution fluorescent …
Super-resolution fluorescence microscopic imaging in pathogenesis and drug treatment of neurological disease
J Gong, Z **, H Chen, J He, Y Zhang… - Advanced Drug Delivery …, 2023 - Elsevier
Since super-resolution fluorescence microscopic technology breaks the diffraction limit that
has existed for a long time in optical imaging, it can observe the process of synapses formed …
has existed for a long time in optical imaging, it can observe the process of synapses formed …
[HTML][HTML] Mitochondrial nucleoid condensates drive peripheral fission through high membrane curvature
Mitochondria are dynamic organelles that undergo fusion and fission events, in which the
mitochondrial membrane and DNA (mtDNA) play critical roles. The spatiotemporal …
mitochondrial membrane and DNA (mtDNA) play critical roles. The spatiotemporal …
A general design of pyridinium-based fluorescent probes for enhancing two-photon microscopy
Two-photon absorbing fluorescent probes have emerged as powerful imaging tools for
subcellular-level monitoring of biological substances and processes, offering advantages …
subcellular-level monitoring of biological substances and processes, offering advantages …
The clinical potential of optogenetic interrogation of pathogenesis
Background Opsin‐based optogenetics has emerged as a powerful biomedical tool using
light to control protein conformation. Such capacity has been initially demonstrated to control …
light to control protein conformation. Such capacity has been initially demonstrated to control …