Evolutionary and population (epi) genetics of immunity to infection

LB Barreiro, L Quintana-Murci - Human genetics, 2020 - Springer
Immune response is one of the functions that have been more strongly targeted by natural
selection during human evolution. The evolutionary genetic dissection of the immune system …

Release of promoter–proximal paused Pol II in response to histone deacetylase inhibition

R Vaid, J Wen, M Mannervik - Nucleic acids research, 2020 - academic.oup.com
A correlation between histone acetylation and transcription has been noted for a long time,
but little is known about what step (s) in the transcription cycle is influenced by acetylation …

H3K4 Methylation in β-Cells Prevents Transcriptional Downregulation and Variance Associated With Type 2 Diabetes

B Vanderkruk, N Maeshima, DJ Pasula, M An… - bioRxiv, 2021 - biorxiv.org
Summary Histone 3 lysine 4 trimethylation (H3K4me3) is associated with promoters of
actively expressed genes, with genes important for cell identity frequently having …

Transcriptional control during the G1 and S phases of the cell cycle in yeast

SL Cooke - 2020 - discovery.ucl.ac.uk
Cell division is a tightly coordinated process that involves doubling of the cellular content
and its separation into two genetically identical daughter cells. In G1 phase of the cell cycle …